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EBV-I3 Polyclonal
Description Epstein-Barr virus-induced gene 3 protein (EBI3), also known as Interleukin-27 subunit beta (IL27B), is a member of the type I cytokine receptor family (Type 3 subfamily) that is composed of two subunits: interleukin-27 (IL-27) and IL-35. EBI3 regulates T-helper cell development, stimulates cytotoxic T-cell activity, suppresses T-cell proliferation, and induces isotype switching in B-cells. EBI3 also plays an important role in its antitumor activity as well as its antiangiogenic activity. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human 
1 ml more info 
14 days 
€361,40 Add to cart -
EBV-I3 Polyclonal
Description Epstein-Barr virus-induced gene 3 protein (EBI3), also known as Interleukin-27 subunit beta (IL27B), is a member of the type I cytokine receptor family (Type 3 subfamily) that is composed of two subunits: interleukin-27 (IL-27) and IL-35. EBI3 regulates T-helper cell development, stimulates cytotoxic T-cell activity, suppresses T-cell proliferation, and induces isotype switching in B-cells. EBI3 also plays an important role in its antitumor activity as well as its antiangiogenic activity. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€174,20 Add to cart -
EBV-LMP [CS1-4]
Description CS1-4 reacts strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. It also reacts with 25 to 50 per cent of EBV-associated undifferentiated nasopharyngeal carcinomas and with Reed Sternberg cells in approximately 90% of EBV-associated Hodgkin’s lymphoma cases. The cocktail recognizes distinct epitopes on the hydrophilic carboxyl region of LMP which is exposed to the cytosol. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human 
1 ml more info 14 days
€361,40 Add to cart -
EBV-LMP [CS1-4]
Description CS1-4 reacts strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. It also reacts with 25 to 50 per cent of EBV-associated undifferentiated nasopharyngeal carcinomas and with Reed Sternberg cells in approximately 90% of EBV-associated Hodgkin’s lymphoma cases. The cocktail recognizes distinct epitopes on the hydrophilic carboxyl region of LMP which is exposed to the cytosol. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
EGFR (E746-A750del Specific) [SP111]
Description Two types of mutations account for approximately 90% of mutated cases: a specific point mutation, L858R, which occurs in exon 21 and short in-frame deletions in exon 19. A common lesion in exon 19 is the deletion of E746-A750, although other variants occur. IHC-based EGFR E746-A750del specific antibody is designed to detect deletion of E746-A750 in exon 19. Deletion in exon 19 is associated with response of non-small cell lung carcinoma (NSCLC) to gefitinib or erlotinib monotherapy. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€455,00 Add to cart -
EGFR (E746-A750del Specific) [SP111]
Description Two types of mutations account for approximately 90% of mutated cases: a specific point mutation, L858R, which occurs in exon 21 and short in-frame deletions in exon 19. A common lesion in exon 19 is the deletion of E746-A750, although other variants occur. IHC-based EGFR E746-A750del specific antibody is designed to detect deletion of E746-A750 in exon 19. Deletion in exon 19 is associated with response of non-small cell lung carcinoma (NSCLC) to gefitinib or erlotinib monotherapy. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
EGFR (L858R Mutant Specific) [MD27R]
Description Two types of mutations account for approximately 90% of mutated cases: a specific point mutation, L858R, which occurs in exon 21 and short in-frame deletions in exon 19. A common lesion in exon 19 is the deletion of E746-A750, although other variants occur. IHC-based EGFR E746-A750del specific antibody is designed to detect deletion of E746-A750 in exon 19. Deletion in exon 19 is associated with response of non-small cell lung carcinoma (NSCLC) to gefitinib or erlotinib monotherapy. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€214,50 Add to cart -
EGFR [GFR/1667]
Description Epidermal growth factor receptor (EGFR) is a 170 kDa transmembrane glycoprotein receptor tyrosine kinase that, activated by epidermal growth factor (EGF), affects cell growth and differentiation. Binding of EGF or TGF alpha to EGFR activates tyrosine kinase activity of the receptor. Phosphorylation of Tyr 992, Tyr 1068 and Tyr 1086 is required for conformational change in the C-terminal of EGFR. Autophosphorylation of Tyr 992 creates a binding site for the phospholipase C-gamma (PLC-gamma) SH2 domain, inducing downstream signaling. In breast cancer, EGFR is predorminately expressed in basal cell-like carcinoma, it has been recommendated for identification of basal-like breast carcinoma along with Cytokeratin 5/6. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
EGFR [GFR/1667]
Description Epidermal growth factor receptor (EGFR) is a 170 kDa transmembrane glycoprotein receptor tyrosine kinase that, activated by epidermal growth factor (EGF), affects cell growth and differentiation. Binding of EGF or TGF alpha to EGFR activates tyrosine kinase activity of the receptor. Phosphorylation of Tyr 992, Tyr 1068 and Tyr 1086 is required for conformational change in the C-terminal of EGFR. Autophosphorylation of Tyr 992 creates a binding site for the phospholipase C-gamma (PLC-gamma) SH2 domain, inducing downstream signaling. In breast cancer, EGFR is predorminately expressed in basal cell-like carcinoma, it has been recommendated for identification of basal-like breast carcinoma along with Cytokeratin 5/6. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
EGFR [MD115R]
Description Epidermal growth factor receptor (EGFR) is a 170 kDa transmembrane glycoprotein receptor tyrosine kinase that, activated by epidermal growth factor (EGF), affects cell growth and differentiation. Binding of EGF or TGF alpha to EGFR activates tyrosine kinase activity of the receptor. Phosphorylation of Tyr 992, Tyr 1068 and Tyr 1086 is required for conformational change in the C-terminal of EGFR. Autophosphorylation of Tyr 992 creates a binding site for the phospholipase C-gamma (PLC-gamma) SH2 domain, inducing downstream signaling. In breast cancer, EGFR is predorminately expressed in basal cell-like carcinoma, it has been recommendated for identification of basal-like breast carcinoma along with Cytokeratin 5/6. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart
