| Quantity | Title | Price |
|---|---|---|
| 1 × | OLA1 protein (His tag) | 0 |
| 1 × | S100A3 protein (His tag) | 0 |
| 1 × | ALG2 antibody | 0 |
| 1 × | ALG2 antibody | 0 |
| 1 × | Goat anti Human IgG (H + L) (HRP) | 0 |
| 1 × | Cholera toxin antibody (B subunit) | 0 |
| 1 × | CLTB protein (His tag) | 0 |
| 1 × | ADPRHL2 protein (His tag) | 0 |
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ROS Polyclonal
Description ROS or ROS1, a 263914 Da cell membrane tyrosine kinase expressed in brain, an orphan receptor tyrosine kinase of the insulin receptor family, was initially identified as a homolog of v-ros from the UR2 sarcoma virus. ROS consists of a large extracellular domain that is composed of six fibronectin repeats, a transmembrane domain, and an intracellular kinase domain. While the function of ROS is undefined, it has been shown to play an important role in differentiation of epididymal epithe. The first oncogenic fusion of ROS, FIG-ROS1, was initially identified by research studies in glioblast, and subsequent studies have found this fusion in cholangiocarcinoa, ovarian can and non-small cell lung cancer (NSCLC). Investigators have found additional oncogenic ROS fusion proteins in NSCLC (at a frequency of ~1.6%), where the ROS1 kinase domain is fused to the amino-terminal region of a number of different proteins, including CD74 and SLC34A. ROS fusion proteins activate the SHP-2 phosphatase, P Host Rabbit Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat 
1 ml more info 
14 days 
€374,40 Add to cart -
ROS Polyclonal
Description ROS or ROS1, a 263914 Da cell membrane tyrosine kinase expressed in brain, an orphan receptor tyrosine kinase of the insulin receptor family, was initially identified as a homolog of v-ros from the UR2 sarcoma virus. ROS consists of a large extracellular domain that is composed of six fibronectin repeats, a transmembrane domain, and an intracellular kinase domain. While the function of ROS is undefined, it has been shown to play an important role in differentiation of epididymal epithe. The first oncogenic fusion of ROS, FIG-ROS1, was initially identified by research studies in glioblast, and subsequent studies have found this fusion in cholangiocarcinoa, ovarian can and non-small cell lung cancer (NSCLC). Investigators have found additional oncogenic ROS fusion proteins in NSCLC (at a frequency of ~1.6%), where the ROS1 kinase domain is fused to the amino-terminal region of a number of different proteins, including CD74 and SLC34A. ROS fusion proteins activate the SHP-2 phosphatase, P Host Rabbit Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat
7 ml more info 14 days
€201,50 Add to cart -
SDF1/CXCL12 Polyclonal
Description The C-X-C or α chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell-derived factor-1, or SDF-1. SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemoattractant for T cells and monocytes, but not neutrophils. Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. Stimulates migration Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€494,00 Add to cart -
Serotonin Polyclonal
Description Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space (>20µm) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with i Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human, Rat
1 ml more info 14 days
€374,40 Add to cart -
Serotonin Polyclonal
Description Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space (>20µm) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with i Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human, Rat
7 ml more info 14 days
€187,20 Add to cart -
SOX11 Polyclonal
Description Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of cyclin D1 (CCND1), an important regulator of the G1/S phase of the cell cycle, due to the specific translocation t(11;14)(q13;q32). Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack cyclin D1 expression and may be misdiagnosed by overreliance on cyclin D1 IHC. Recently, SOX-11 protein expression in MCL has been investigated by immunohistochemistry. Two studies have evaluated SOX-11 expression in MCL and found strong nuclear expression of SOX-11 in almost all cyclin D1-positive MCL (93%-100%). In all 13 cases of cyclin D1-negative MCL, SOX-11 was strongly expressed. The authors also found that blastoid variant of MCL can be differentiated from CD5+ diffuse large B cell lymphoma, which was negative for SOX-11. In summary, nuclear protein expression of SOX-11 is highly associated with both cyclin Host Rabbit Application Peptide ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse,Rat, Bovine,Pig (Porcine)
1 ml more info 14 days
€374,40 Add to cart -
SOX11 Polyclonal
Description Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of cyclin D1 (CCND1), an important regulator of the G1/S phase of the cell cycle, due to the specific translocation t(11;14)(q13;q32). Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack cyclin D1 expression and may be misdiagnosed by overreliance on cyclin D1 IHC. Recently, SOX-11 protein expression in MCL has been investigated by immunohistochemistry. Two studies have evaluated SOX-11 expression in MCL and found strong nuclear expression of SOX-11 in almost all cyclin D1-positive MCL (93%-100%). In all 13 cases of cyclin D1-negative MCL, SOX-11 was strongly expressed. The authors also found that blastoid variant of MCL can be differentiated from CD5+ diffuse large B cell lymphoma, which was negative for SOX-11. In summary, nuclear protein expression of SOX-11 is highly associated with both cyclin Host Rabbit Application Peptide ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse,Rat, Bovine,Pig (Porcine)
7 ml more info 14 days
€187,20 Add to cart -
SSR2/TRAP Beta Polyclonal
Description Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of proteins that have been designated Stats (signal transducers and activators of transcription. The first members of this family to be described include Stat1α p91, Stat1β p84 (a form of p91 that lacks 38 COOH-terminal amino acids) and Stat2 p113. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Stat3, which becomes activated in response to epidermal growth factor (EGF) and interleukin-6 (IL-6), but not interferon-γ (IFN-γ) or Stat4, is an The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2).The signal sequence receptor Host Rabbit Application Flow cytometry (FC), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€520,00 Add to cart -
Toxoplasma Gondii Polyclonal
Description Toxoplasma is a crescent shaped sporozoan that lives as an intracellular parasite in various tissues of many vertebrates and completes its life cycle in a single host. Its life cycle includes two phases called the intestinal (or enteroepithelial) and extraintestinal phases. The intestinal phase produces oocysts and occurs only in cats, wild as well as domesticated. The extraintestinal phase occurs in all infected animals including cats, and produces tachyzoites (actively proliferating trophozoites) and eventually, bradyzoites (slowly growing trophozoites) or zoitocysts. Infection due to Toxoplasma gondii occurs in pregnant women where a variable degree of immunosuppression may exist or in patients receiving immunosuppressive drug therapy. Toxoplasma infects tissue of the GI tract where an active infection is accompanied by fever and enlargement of the spleen. Symptoms of toxoplasmosis are generally mild but severe infection of lymph nodes may occur. Congenital toxoplasmosis, in which t Host Rabbit Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Whole organisms
1 ml more info 14 days
€374,40 Add to cart -
Treponema Pallidum/Syphilis Polyclonal
Description Treponema pallidum is a species of spirochaete bacterium with subspecies that cause treponemal diseases such as syphilis, bejel, pinta and yaws. It is not seen on a Gram stained smear because the organism has a waxy coat around it that does not accept the Gram stain. Treponema pallidum is a Gram-negative spirochaete bacterium with periplasmic flagella. There are at least five subspecies of T. pallidum, including T. pallidum pallidum (the cause of syphilis), T. pallidum pertenue (the cause of yaws), T. pallidum carateum (the cause of pinta), T. pallidum trirocllium (the cause of syphilis and pinta) and T. pallidum endemicum (the cause of bejel). T. pallidum is motile and is generally transmitted through close sexual contact, entering the host via breaches in squamous or columnar epithelium. The microbe can also be transferred to a fetus by transplacental passage during the later stages of pregnancy, causing congenital syphilis. T. pallidum has one of the shortest bacterial genomes at on Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Treponema pallidum
1 ml more info 14 days
€374,40 Add to cart
