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  • Article number: 10R-P136C
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    PAPPA antibody

    Description Mouse monoclonal PAPPA antibody (Shipping Cost: €205.00)
    Host Mouse
    Application ELISA,Immunoprecipitation (IP),Western Blot (WB)
    Concentration Batch dependent - please inquire should you have specific requirements
    Specificity Human
    Unit 1 mg
    more info
    Normal leadtime 5-7 days
    Calculated total €405,00 
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  • Article number: MC0177
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    HDAC1/HD1 [10E2]

    Description Acetylation of the histone tail causes chromatin to adopt an “open” conformation, allowing increased accessibility of transcription factors to DNA. The identification of histone acetyltransferases (HATs) and their large multiprotein complexes has yielded important insights into how these enzymes regulate transcription. HAT complexes interact with sequence-specific activator proteins to target specific genes. In addition to histones, HATs can acetylate non-histone proteins, suggesting multiple roles for these enzymes. In contrast, histone deacetylation promotes a “closed” chromatin conformation and typically leads to repression of gene activity. Mammalian histone deacetylases can be divided into three classes on the basis of their similarity to various yeast deacetylases. Class I (HDACs 1, 2, 3 and 8) proteins are related to the yeast Rpd3-like proteins, those in class II (HDACs 4, 5, 6, 7, 9 and 10) are related to yeast Hda1-like proteins and class III proteins are related to the yeast
    Host Mouse
    Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
    Reactivity Human, Mouse, Rat
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €361,40 
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