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TCR γ/δ (TCR gamma/delta) [H41]
Description T-cell receptor (TCR), a heterodimer composed of either α and β or γ and δ chains, recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Most human T cells (95%) express the α/β or either CD4 or CD8 molecule (single positive, SP), while 2-5% express the γ/δ. However, a small number of T cells lack both CD4 and CD8 (double negative, DN). T helper cells express CD4 proteins and T cytotoxic cells display CD8. Increased percentages of α/β DN T cells have been identified in some autoimmune and immunodeficiency disorders. γ/δ T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than α/β T cells. Subsets of γ/δ T cells have shown antitumor and immunoregulatory activity. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human -
Monoclonal antibody to monkey CD3 (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in immunohistochemical staining of frozen tissues, flow cytometric analysis and intracellular staining. Further, the antibody is able to stimulate rhesus macaque PBMC. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus monkey and baboon CD3. Other available formats: biotin labeled (cat. no. CT162) and FITC labeled (cat. no. CT163). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon -
Monoclonal antibody to monkey CD3 biotin (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in flow cytometric analysis. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus macaque and baboon CD3. Other available formats: unconjugated (cat. no.CT161) and FITC labeled (cat. no.CT163). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon Conjugate Biotin -
Monoclonal antibody to monkey CD3 FITC (clone FN-18)
Description The monoclonal antibody to monkey CD3 (clone FN-18) was first described in 1986. The FN-18 antibody can be used in flow cytometric analysis. The FN-18 antibody has been reported to cross react with rhesus macaque, cynomolgus macaque and baboon CD3. Other available formats: unconjugated (cat. no. CT161) and biotin labeled (cat. no. CT162). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC) Reactivity Rhesus Macaque,Cynomolgus Monkey,Baboon Conjugate FITC -
Monoclonal antibody to human IFN-gamma (clone MD-1)
Description The monoclonal antibody to human IFN-γ (clone MD-1) was first described in 1985. It has shown to neutralize the antiviral activity of both natural and recombinant human IFN-γ and in a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-γ. The MD-1 antibody has been descripted as useful in a sandwich ELISA and in ELISPOT assays. Further, the antibody has proven to cross react with chimpanzee and rhesus macaque IFN-γ and can be used for immunohistochemical staining of frozen tissues. The MD-1 antibody has been reported for use in intracellular flow cytometric analysis and in Luminex systems. Other available formats: biotin labeled (cat. no. CT218) and FITC labeled (cat. no. CT220). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application ELISA,Enzyme-linked immunosorbent spot (ELISPOT),Flow cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs),Neutralization (Neut),Western Blot (WB) Reactivity Chimpanzee,Rhesus Macaque -
Monoclonal antibody to human IFN-gamma biotin (clone MD-1)
Description The monoclonal antibody to human IFN-γ was first described in 1985. It has shown to neutralize the antiviral activity of both natural and recombinant human IFN-γ and in a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-γ. The MD-1 antibody has been descripted as useful in a sandwich ELISA. Further, the antibody has proven to cross react with rhesus macaque IFN-γ and can be used for immunohistochemical staining of frozen tissues. The MD-1 antibody has been reported for use in intracellular flow cytometric analysis. Other available formats: unconjugated (cat. no. CT215) and FITC labeled (cat. no. CT220). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application ELISA,Flow cytometry (FC) Reactivity Chimpanzee,Rhesus Macaque Conjugate Biotin -
Monoclonal antibody to human IFN-gamma FITC (clone MD-1)
Description The monoclonal antibody to human IFN-γ (clone MD-1) was first described in 1985. It has shown to neutralize the antiviral activity of both natural and recombinant human IFN-γ and in a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-γ. The antibody has proven to cross react with chimpanzee and rhesus macaque IFN-γ and can be used for immunohistochemical staining of frozen tissues. The MD-1 antibody has been reported for use in intracellular flow cytometric analysis. Other available formats: unconjugated (cat. no. CT215) and biotin labeled (cat. no. CT218). (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application Flow cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs) Reactivity Chimpanzee,Rhesus Macaque Conjugate FITC -
Monoclonal antibody to human IFN-gamma (clone MD-2)
Description The monoclonal antibody to human IFN-γ (clone MD-2) was first described in 1985. It has shown to binds with high affinity to both natural and recombinant human IFN-γ but does not neutralize the antiviral bioactivity of IFN-γ in vitro. In a Western Blot the antibody reacts with the 20 kDa and 25 kDa polypeptides present in natural human IFN-γ. The MD-2 antibody has been descripted as useful in a sandwich ELISA. Further, the antibody has proven to cross react with rhesus macaque, cynomolgus monkey and marmoset IFN-γ and can be used for immunohistochemical staining of frozen tissues. (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application ELISA,Immunohistochemistry on frozen sections (IHC-Fs),Western Blot (WB) Reactivity Rhesus Macaque,Cynomolgus Monkey,Marmoset -
Monoclonal antibody to monkey IFN-gamma (clone MD-1)
Description The neutralizing monoclonal antibody to monkey IFN-γ (clone MD-1) was first described in 1985. The MD-1 antibody can be used in a sandwich ELISA and in ELISPOT assays. Further, the antibody has been descripted in immunohistochemical staining of frozen tissues of marmosets and in intracellular flow cytometric analysis. The MD-1 antibody has been reported to cross react with rhesus macaque, pig-tailed macaque, cynomogus monkey, baboon and African green monkey IFN-γ and can be used in Luminex systems. (Shipping cost: €30.00; Handling cost €30.00 - €50.00) Host Mouse Application ELISA,Enzyme-linked immunosorbent spot (ELISPOT),Flow cytometry (FC),Immunohistochemistry on frozen sections (IHC-Fs),Neutralization (Neut),Western Blot (WB) Reactivity Rhesus Macaque,Cynomolgus Monkey,Pig-tailed Macaque,Japanese Macaque,Crested Black Macaque,Barbary Macaque,Lion-tailed Macaque,Baboon,Mandrill,African Green Monkey (Chlorocebus),Black Mangabey -
Monoclonal antibody to rat IFN-gamma (clone DB-1)
Description The mouse anti-rat IFN-γ monoclonal antibody (clone DB-1) was first described by Van der Meide P.H. et al. in 1989. The rat IFN-γ antibody is of the IgG1 subtype and neutralizes both natural and recombinant rat IFN-γ and mouse IFN-γ in vitro and in vivo. In Western blot analysis the DB-1 antibody reacts with the 14 kDa and 18 kDa polypeptides present in rat IFN-γ with moderate activity. Clone DB-1 has shown not to bind with rat IFN-α and IFN-β nor human IFNs. Further, biotinyated DB-1 antibody (cat. no. CT035) is highly effective as detector antibody in both sandwich ELISA and ELISPOT assays using DB-12 (cat no. CT052) as coating antibody. Also the reverse combination in which the DB-1 antibody functions as coating antibody and biotinylated DB-12 antibody (cat. no. CT033) or biotinylated polyclonal antibody to rat IFN-γ as detector antibody can be used in an ELISA and ELISPOT systems. The DB-1 antibody is also applicable in immunohistochemistry on frozen tissues and intracellular stain Host Mouse Application ELISA,Enzyme-linked immunosorbent spot (ELISPOT),Immunohistochemistry on frozen sections (IHC-Fs),Neutralization (Neut),Western Blot (WB)