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Uroplakin II [EPR18799]
Description Uroplakin II is a 15 kDa protein component of urothelial plaques. Studies have shown Uroplakin II mRNA was highly specific and was expressed in both bladder cancer tissues and peripheral blood of patients with primary and metastatic urothelial carcinoma of the bladder. Uroplakin II is a highly specific and may be useful in identifying tumors of urothelial origin. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human 
7 ml more info 
14 days 
€247,00 Add to cart -
Uroplakin III [EPR14420]
Description Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In non-neoplastic mammalian urothelium, UPs are expressed in the luminal surface plasmalemma of superficial (umbrella) cells, forming complexes of 16 nm crystalline particles. Moll et al. reported that UPIII was detectable immunohistochemically in 29 of 55 primary (53%) and 23 of 35 metastatic (66%) urothelial carcinomas, whereas many non- urothelial carcinomas were UPIII-negative. The authors concluded that anti-UPIII should be a valuable marker, especially for the specific identification of urothelial carcinomas in patients with metastases of unknown primary site. Subsequently, Olsburgh et al. studied UP gene expression in normal urothelium and bladder cancer specimens, and found that expression was absent after malignant transformation. Ohtsuka et al. concluded in their studies that UPIII expression was strongly associated with lower tumor Host Rabbit Application Flow cytometry (FC), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
Uroplakin III [EPR14420]
Description Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In non-neoplastic mammalian urothelium, UPs are expressed in the luminal surface plasmalemma of superficial (umbrella) cells, forming complexes of 16 nm crystalline particles. Moll et al. reported that UPIII was detectable immunohistochemically in 29 of 55 primary (53%) and 23 of 35 metastatic (66%) urothelial carcinomas, whereas many non- urothelial carcinomas were UPIII-negative. The authors concluded that anti-UPIII should be a valuable marker, especially for the specific identification of urothelial carcinomas in patients with metastases of unknown primary site. Subsequently, Olsburgh et al. studied UP gene expression in normal urothelium and bladder cancer specimens, and found that expression was absent after malignant transformation. Ohtsuka et al. concluded in their studies that UPIII expression was strongly associated with lower tumor Host Rabbit Application Flow cytometry (FC), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€247,00 Add to cart -
USP6NL/RNTRE Polyclonal
Description Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 14 days
€520,00 Add to cart -
VEGFC (Flt4L) Polyclonal
Description Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€494,00 Add to cart -
VEGFC (Flt4L) Polyclonal
Description Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
7 ml more info 14 days
€201,50 Add to cart -
VIP Polyclonal
Description Vasoactive intestinal peptide (VIP) is a 28 amino acid neuropeptide that has been isolated from various organs like intestine the brain upper respiratory and nasal mucosa, salivary glands, and the male and female genital tracts. It is also identifiable in human eosinophils, polymorphonuclear and mononuclear leucocytes. VIP is also known as a potent stimulant of mucous secretion, vasodilatation, and smooth muscle relaxation in bronchus and many other organs. According to various studies, VIP also has effects on the immune regulation. In the murine immune system, VIP inhibited the proliferative responses of lymphocytes to the T cell mitogens. VIP is also known to have altered preferentially IgA synthesis by lymphocytes from gastrointestinal tissues and spleen. In the human immune system, VIP is known to have inhibited the proliferative response of T lymphocytes to mercuric chloride, and inhibited natural killer (NK) cell function. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
VIP Polyclonal
Description Vasoactive intestinal peptide (VIP) is a 28 amino acid neuropeptide that has been isolated from various organs like intestine the brain upper respiratory and nasal mucosa, salivary glands, and the male and female genital tracts. It is also identifiable in human eosinophils, polymorphonuclear and mononuclear leucocytes. VIP is also known as a potent stimulant of mucous secretion, vasodilatation, and smooth muscle relaxation in bronchus and many other organs. According to various studies, VIP also has effects on the immune regulation. In the murine immune system, VIP inhibited the proliferative responses of lymphocytes to the T cell mitogens. VIP is also known to have altered preferentially IgA synthesis by lymphocytes from gastrointestinal tissues and spleen. In the human immune system, VIP is known to have inhibited the proliferative response of T lymphocytes to mercuric chloride, and inhibited natural killer (NK) cell function. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€163,80 Add to cart -
Wilms' Tumor (WT1) [EP122]
Description WT1 is a suppressor gene located on chromosome 11p13. Wilms’ Tumor protein (WT1) has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
Wilms' Tumor (WT1) [EP122]
Description WT1 is a suppressor gene located on chromosome 11p13. Wilms’ Tumor protein (WT1) has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart
