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TFF3 [EPR3974]
Description refoil factors (TFFs) constitute a family of mucin-associated peptides containing one or more structurally characteristic trefoil domains. Trefoil factor 3 (TFF3) is a member of the trefoil family. They are mainly synthesized and secreted by mucin secreting epithelial cells lining the gastrointestinal tract and have a close association with mucins. TFF3 is expressed in goblet cells of the intestines and colon, eptihelial cells of the breast, prostate, thyroid, salivary gland and urinary tract. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human 
7 ml more info 
14 days 
€254,80 Add to cart -
TIA1 [MD173R]
Description T-cell-restricted intracellular antigen-1 (TIA1), also known as nucleolysin TIA1 isoform p40, is a member of a RNA-binding protein family. It possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis, as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
TIA1 [MD173R]
Description T-cell-restricted intracellular antigen-1 (TIA1), also known as nucleolysin TIA1 isoform p40, is a member of a RNA-binding protein family. It possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis, as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€214,50 Add to cart -
Toxoplasma Gondii Polyclonal
Description Toxoplasma is a crescent shaped sporozoan that lives as an intracellular parasite in various tissues of many vertebrates and completes its life cycle in a single host. Its life cycle includes two phases called the intestinal (or enteroepithelial) and extraintestinal phases. The intestinal phase produces oocysts and occurs only in cats, wild as well as domesticated. The extraintestinal phase occurs in all infected animals including cats, and produces tachyzoites (actively proliferating trophozoites) and eventually, bradyzoites (slowly growing trophozoites) or zoitocysts. Infection due to Toxoplasma gondii occurs in pregnant women where a variable degree of immunosuppression may exist or in patients receiving immunosuppressive drug therapy. Toxoplasma infects tissue of the GI tract where an active infection is accompanied by fever and enlargement of the spleen. Symptoms of toxoplasmosis are generally mild but severe infection of lymph nodes may occur. Congenital toxoplasmosis, in which t Host Rabbit Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Whole organisms 
1 ml more info 14 days
€374,40 Add to cart -
TPO/Thyroid Peroxidase [MD118R]
Description Thyroid Peroxidase (TPO) is a membrane-bound protein, catalyzing iodide oxidation, iodination of tyrosine residues and generation of triiodothyronine and thyroxine. It is first synthesized within the endoplasmic reticulum (ER), where it can be readily detected. After folding to the native state within the ER, intracellular transport of TPO to the cell surface occurs via the Golgi complex, a compartment typically associated with N-glycan processing of many cell surface glycoproteins. TPO labels normal thyroid epithelial cells and thyroid tumor cells. The expression level in thyroid carcinomas is lower than that of normal and benign thyroid tumors. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€416,00 Add to cart -
TPO/Thyroid Peroxidase [MD118R]
Description Thyroid Peroxidase (TPO) is a membrane-bound protein, catalyzing iodide oxidation, iodination of tyrosine residues and generation of triiodothyronine and thyroxine. It is first synthesized within the endoplasmic reticulum (ER), where it can be readily detected. After folding to the native state within the ER, intracellular transport of TPO to the cell surface occurs via the Golgi complex, a compartment typically associated with N-glycan processing of many cell surface glycoproteins. TPO labels normal thyroid epithelial cells and thyroid tumor cells. The expression level in thyroid carcinomas is lower than that of normal and benign thyroid tumors. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Transcription Factor PU.1/PU.1/Spi1 [EP18]
Description PU.1 is a member of the Ets family of transcription factors and is required for the development of multiple hematopoietic lineages. It plays a pivotal role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development. PU.1 stains B lymphocytes in germinal center and mantle B cells, but not plasma cells. It labels many types of B-cell lymphomas including mantle cell lymphoma, but is not expressed in classical Hodgkin lymphoma (cHL). The lack of transcription factor PU.1 protein expression in cHL, a lymphoproliferative disease of predominantly B-cell origin, likely contributes to the lack of immunoglobulin expression and incomplete B-cell phenotype characteristic of the Reed-Sternberg cells in cHL. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
Transcription Factor PU.1/PU.1/Spi1 [EP18]
Description PU.1 is a member of the Ets family of transcription factors and is required for the development of multiple hematopoietic lineages. It plays a pivotal role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development. PU.1 stains B lymphocytes in germinal center and mantle B cells, but not plasma cells. It labels many types of B-cell lymphomas including mantle cell lymphoma, but is not expressed in classical Hodgkin lymphoma (cHL). The lack of transcription factor PU.1 protein expression in cHL, a lymphoproliferative disease of predominantly B-cell origin, likely contributes to the lack of immunoglobulin expression and incomplete B-cell phenotype characteristic of the Reed-Sternberg cells in cHL. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Treponema Pallidum/Syphilis Polyclonal
Description Treponema pallidum is a species of spirochaete bacterium with subspecies that cause treponemal diseases such as syphilis, bejel, pinta and yaws. It is not seen on a Gram stained smear because the organism has a waxy coat around it that does not accept the Gram stain. Treponema pallidum is a Gram-negative spirochaete bacterium with periplasmic flagella. There are at least five subspecies of T. pallidum, including T. pallidum pallidum (the cause of syphilis), T. pallidum pertenue (the cause of yaws), T. pallidum carateum (the cause of pinta), T. pallidum trirocllium (the cause of syphilis and pinta) and T. pallidum endemicum (the cause of bejel). T. pallidum is motile and is generally transmitted through close sexual contact, entering the host via breaches in squamous or columnar epithelium. The microbe can also be transferred to a fetus by transplacental passage during the later stages of pregnancy, causing congenital syphilis. T. pallidum has one of the shortest bacterial genomes at on Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Treponema pallidum
1 ml more info 14 days
€374,40 Add to cart -
TTF2/FOXE1 Polyclonal
Description Probable transcription factor. Could be involved in thyroid gland organogenesis. Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas. Defects in FOXE1 are the cause of Bamforth-Lazarus syndrome (BLS). BLS is associated with thyroid agenesis, cleft palate and choanal atresia. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse
1 ml more info 14 days
€455,00 Add to cart
