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C4d [SP91]
Description Complement component 4, or C4, plays a central role in the complement system. C4d is the final proteolytic remnant of deposited C4b on endothelium and remains covalently attached to endothelium for little more than a week. It is easily detectable by Immunohistochemistry. This antibody combined with anti-C3d can be utilized as a tool for diagnosis of AR (Acute Rejection) and warrant prompt and aggressive anti-rejection treatment. C4d can be detected in peritubular capillaries in both chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival and is an aid in treating acute rejection. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 
14 days 
€455,00 Add to cart -
C4d [SP91]
Description Complement component 4, or C4, plays a central role in the complement system. C4d is the final proteolytic remnant of deposited C4b on endothelium and remains covalently attached to endothelium for little more than a week. It is easily detectable by Immunohistochemistry. This antibody combined with anti-C3d can be utilized as a tool for diagnosis of AR (Acute Rejection) and warrant prompt and aggressive anti-rejection treatment. C4d can be detected in peritubular capillaries in both chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival and is an aid in treating acute rejection. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Cadherin-E/CD324 [MD128R]
Description E-Cadherin is a transmembrane glycoprotein, plays an important role in epithelial cell adhesion. A decreased expression of E-Cadherin is associated with metastatic potential and poor prognosis in breast cancer and esophagus cancer. In combination with p120 Catenin or Cytokeratin, it is useful for the differentiation between ductal (E-Cadherin positive) and lobular (E-Cadherin negative) breast carcinomas. It may also help in diagnosis of mesothelioma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Cadherin-E/CD324 [MD128R]
Description E-Cadherin is a transmembrane glycoprotein, plays an important role in epithelial cell adhesion. A decreased expression of E-Cadherin is associated with metastatic potential and poor prognosis in breast cancer and esophagus cancer. In combination with p120 Catenin or Cytokeratin, it is useful for the differentiation between ductal (E-Cadherin positive) and lobular (E-Cadherin negative) breast carcinomas. It may also help in diagnosis of mesothelioma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Cadherin-K/CDH6 [MD129R]
Description Cadherin-6 is a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. It is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Cadherin-6 is highly expressed in kidney and the central nervous system. It has been found to be related to fetal kidney development and has been identified as a major cadherin in renal proximal tubules where conventional renal cell carcinoma originates. The expression of Cadherin-6 is associated with tumor progression in renal cell carcinoma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
Cadherin-K/CDH6 [MD129R]
Description Cadherin-6 is a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. It is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Cadherin-6 is highly expressed in kidney and the central nervous system. It has been found to be related to fetal kidney development and has been identified as a major cadherin in renal proximal tubules where conventional renal cell carcinoma originates. The expression of Cadherin-6 is associated with tumor progression in renal cell carcinoma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Cadherin-ksp [MD127R]
Description Kidney-specific cadherin, also known as Cadherin-16, is a member of the calcium dependent family of adhesion molecules that play important roles during embryonic development, maintenance of tissue architecture and growth control during tumorigenesis. In the kidney, Ksp-cadherin expression is uniquely localized predominantly in the distal portion of the nephron. There are four major subtypes of renal neoplasms; clear cell and papillary renal cell carcinoma are thought to be of proximal tubular origin, while oncocytoma and chromophobe renal cell carcinoma (RCC) are derived from cells of the distal nephron. Studies have shown high sensitivity and specificity of Ksp-cadherin to chromophobe RCC (86-100%) and oncocytoma (76-95%). Conversely, low reactivity was observed with clear cell RCC (14-30%) and papillary RCC (0-13%), supporting the use of Ksp-cadherin as a marker for the distal portion of the nephron, and for its use as an adjunct for the detection of chromophobe RCC and oncocytoma. ( Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Caldesmon [EP19]
Description Caldesmon is a smooth muscle regulatory protein that interacts with actin, myosin, tropomyosin, and calmodulin. It is more specific to smooth muscle differentiation than desmin and muscle specific actin. Also, it is useful in differentiation of smooth muscle from myofibroblast tumors, uterus leiomyoma from endometrial stroma tumor. Caldesmon is a marker for identification of epitheloid mesothelioma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€508,30 Add to cart -
Caldesmon [EP19]
Description Caldesmon is a smooth muscle regulatory protein that interacts with actin, myosin, tropomyosin, and calmodulin. It is more specific to smooth muscle differentiation than desmin and muscle specific actin. Also, it is useful in differentiation of smooth muscle from myofibroblast tumors, uterus leiomyoma from endometrial stroma tumor. Caldesmon is a marker for identification of epitheloid mesothelioma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Calponin [MD130R]
Description Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein thought to be involved in regulation of actomyosin as well as the regulation or modulation of contraction. It is expressed on smooth muscle cells and myoepithelial cells. Calponin has been used to identify invasion of breast lesion. Additionally, Calponin is expressed on malignant fibrous histiocytoma of bone and adenoid cystic carcinoma of salivary gland. The consistently positive staining pattern in adenoid cystic carcinomas may be useful in discriminating histologically similar but consistently negative polymorphous low-grade adenocarcinomas (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart
