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1 × | FITC anti-mouse CD63 | 0 |
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GATA3 [MD22R]
Description GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50kD anuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67% of urothelial Carcinomas, but none of prostate or renal carcinomas. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
GCDFP-15 [PIP/1571]
Description Gross cystic disease fluid protein (GCDFP-15), also called prolactininducible protein (PIP), is a single polypeptide chain with a versatile function in human reproductive and immunological systems. GCDFP-15 binds to CD4, exerts a potent inhibition on T lymphocyte apoptosis mediated by CD4/T-cell receptor (TCR) activation, and carries a fibronectin-specific aspartyl protease activity. It is up regulated by prolactin and androgens, while it is down regulated by estrogen. In normal adult tissues, GCDFP-15 expression was found in all apocrine, lacrimal, ceruminous, and Moll's glands and in numerous serous cells of the submandibular, sublingual, and minor salivary glands. The serous cells of nasal and bronchial glands were also positive. It is used as a marker of apocrine differentiation. GCDFP-15 has been found in the cyst fluid of cystic breast disease and primary and metastatic breast cancer, and considered a highly specific marker for identification of breast cancer. GCDFP-15 expression Host Rabbit Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
GCDFP-15 [PIP/1571]
Description Gross cystic disease fluid protein (GCDFP-15), also called prolactininducible protein (PIP), is a single polypeptide chain with a versatile function in human reproductive and immunological systems. GCDFP-15 binds to CD4, exerts a potent inhibition on T lymphocyte apoptosis mediated by CD4/T-cell receptor (TCR) activation, and carries a fibronectin-specific aspartyl protease activity. It is up regulated by prolactin and androgens, while it is down regulated by estrogen. In normal adult tissues, GCDFP-15 expression was found in all apocrine, lacrimal, ceruminous, and Moll's glands and in numerous serous cells of the submandibular, sublingual, and minor salivary glands. The serous cells of nasal and bronchial glands were also positive. It is used as a marker of apocrine differentiation. GCDFP-15 has been found in the cyst fluid of cystic breast disease and primary and metastatic breast cancer, and considered a highly specific marker for identification of breast cancer. GCDFP-15 expression Host Rabbit Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human -
GFAP [MD104R]
Description Glial fibrillary acidic protein (GFAP) is the subunit of the glial specific “intermediate” filament that include desmin filaments in smooth muscle, vimentin filaments in cultured fibroblasts, keratin filaments in epithelium and neurofilaments in neural cells. GFAP is a major product of astrocytic differentiation. Compared with special stains currently used to identify an astroglial component in brain tumors, GFAP staining is more sensitive. Further, the immunohistochemical staining method is useful in demonstrating reactive astrocytes, whether secondary to a brain tumor or to any other neuro-pathological condition. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
GFAP [MD104R]
Description Glial fibrillary acidic protein (GFAP) is the subunit of the glial specific “intermediate” filament that include desmin filaments in smooth muscle, vimentin filaments in cultured fibroblasts, keratin filaments in epithelium and neurofilaments in neural cells. GFAP is a major product of astrocytic differentiation. Compared with special stains currently used to identify an astroglial component in brain tumors, GFAP staining is more sensitive. Further, the immunohistochemical staining method is useful in demonstrating reactive astrocytes, whether secondary to a brain tumor or to any other neuro-pathological condition. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
Glucagon [EP3070]
Description Glucagon is synthesized and released by the alpha-cells of the islets of Langerhans in pancreas. It regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis, stimulates fluid secretions from the intestine and suppresses the release of gastrin. Anti-glucagon is useful in identification of glucagonoma (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
Glucagon [EP3070]
Description Glucagon is synthesized and released by the alpha-cells of the islets of Langerhans in pancreas. It regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis, stimulates fluid secretions from the intestine and suppresses the release of gastrin. Anti-glucagon is useful in identification of glucagonoma (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
Glut1 [EP141]
Description Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1, also known as SCL2A1, is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung , bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiatiation of malignant mesothelioma (positive) from reactive mesothelium (negative). (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
Glut1 [EP141]
Description Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1, also known as SCL2A1, is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung , bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiatiation of malignant mesothelioma (positive) from reactive mesothelium (negative). (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human -
HER2 [EP3]
Description HER-2 neu (also known as c-erbB-2) is a member of the epidermal growth factor receptor (EGFR) family. It is a cell membrane surface-bound tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human