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Cytokeratin 14 [MD187R]
Description Cytokeratin 14 (CK14) is a 50-kDa keratin expressed in abundance in stratified epithelial cells, epidermal cells, basal cells, mesothelial cells, and myoepithelial cells in various tissues including breast and prostate. CK14 is helpful in the identification of breast cancer with basal phenotype. It has been reported that cytokeratin 5/14-positive breast cancers are true basal phenotype confined to BRCA1 tumors. Along with p63 and CK5, CK14 has been a useful marker for cells with basal, squamous and myoepithelial differentiation. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat 
1 ml more info 
14 days 
€416,00 Add to cart -
Cytokeratin 14 [MD187R]
Description Cytokeratin 14 (CK14) is a 50-kDa keratin expressed in abundance in stratified epithelial cells, epidermal cells, basal cells, mesothelial cells, and myoepithelial cells in various tissues including breast and prostate. CK14 is helpful in the identification of breast cancer with basal phenotype. It has been reported that cytokeratin 5/14-positive breast cancers are true basal phenotype confined to BRCA1 tumors. Along with p63 and CK5, CK14 has been a useful marker for cells with basal, squamous and myoepithelial differentiation. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
7 ml more info 14 days
€234,00 Add to cart -
Cytokeratin 15 [MD90R]
Description Cytokeratin 15 (CK15) is involved in the development of stratified epithelia from one-layered polar epithelia and continues to be expressed in several adult epithelial tissues. It labels the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Although CK15 in normal hair follicles was virtually absent from hair bulbs, it was expressed by a subset of keratinocytes in the outer root sheath. In human conjunctival epithelium, strong expression of CK15 was observed in basal cells, whereas Cytokeratin 19 was expressed in both basal and suprabasal layers. CK15 may be used to differentiate primary from metastatic skin cancer. It may be a useful stem cell marker for hair follicle and breast epithelium. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Cytokeratin 15 [MD90R]
Description Cytokeratin 15 (CK15) is involved in the development of stratified epithelia from one-layered polar epithelia and continues to be expressed in several adult epithelial tissues. It labels the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Although CK15 in normal hair follicles was virtually absent from hair bulbs, it was expressed by a subset of keratinocytes in the outer root sheath. In human conjunctival epithelium, strong expression of CK15 was observed in basal cells, whereas Cytokeratin 19 was expressed in both basal and suprabasal layers. CK15 may be used to differentiate primary from metastatic skin cancer. It may be a useful stem cell marker for hair follicle and breast epithelium. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Cytokeratin 16 [MD91R]
Description Cytokeratin 16 (CK16), also known as keratin 16, is a member of the large intermediate filament protein family that form the cytoskeleton. This family is subdivided into acidic (type I) and basic (type II) cytokeratins, but are obligatory heteropolymers, where expression of at least one member of each subfamily is required for filament formation. CK16 is classified as type I, pairing with type II cytokeratin 6. In normal tissues, CK16 is constitutively expressed at low levels in the palmar and plantar epidermis, tongue, oral mucosa, and hair follicles. Studies have proposed a modulatory role of CK16 in cell proliferation, suggesting its utility as a marker for proliferation. Rapid induction of CK16 expression near the edge of wounds, up regulation in response to epidermal growth factor stimulus, and overexpression in hyperproliferative disorders, including psoriasis and chronic contact dermatitis, support this assertion. In psoriasis, the severity of disease is correlated with the amou Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Cytokeratin 18 [MD92R]
Description Cytokeratin 18 (CK18) is intermediate filament phosphoglycoprotein that is expressed in simple and glandular and transitional epithelial cells but not in stratified epithelial cells. CK18 is often co-expressed with CK8. CK8/18 is the major keratin pair in simple-type epithelia. Adenocarcinomas originated from simple and glandular epithelium showed CK18 positive staining. In squamous carcinoma, poorly differentiated tumor cells show CK18 reactivity. Loss of CK 18 expression is associated with progression of breast carcinoma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Cytokeratin 18 [MD92R]
Description Cytokeratin 18 (CK18) is intermediate filament phosphoglycoprotein that is expressed in simple and glandular and transitional epithelial cells but not in stratified epithelial cells. CK18 is often co-expressed with CK8. CK8/18 is the major keratin pair in simple-type epithelia. Adenocarcinomas originated from simple and glandular epithelium showed CK18 positive staining. In squamous carcinoma, poorly differentiated tumor cells show CK18 reactivity. Loss of CK 18 expression is associated with progression of breast carcinoma. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Cytokeratin 19 [MD93R]
Description Cytokeratin polypeptide 19 (CK19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. CK19 is synthesized mainly in embryonic and adult simple epithelia, but has also been found in non-keratinizing stratified epithelia as well. CK19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is different from other keratin-encoding genes. CK19 antibody is a useful tool for the identification of epithelial tumors. It is helpful in distinguishing hepatocellular carcinoma (CK19-) from cholangiocarcinoma (CK19+) or metastatic carcinoma in liver (CK19+). (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Cytokeratin 19 [MD93R]
Description Cytokeratin polypeptide 19 (CK19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. CK19 is synthesized mainly in embryonic and adult simple epithelia, but has also been found in non-keratinizing stratified epithelia as well. CK19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is different from other keratin-encoding genes. CK19 antibody is a useful tool for the identification of epithelial tumors. It is helpful in distinguishing hepatocellular carcinoma (CK19-) from cholangiocarcinoma (CK19+) or metastatic carcinoma in liver (CK19+). (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Cytokeratin 5 [EP24]
Description Keratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. The mitotically active basal layers of most stratified squamous epithelia express 10% to 30% of their total protein as keratin. The two keratins specifically expressed in these cells are the type II keratin CK5 and its corresponding partner, type I keratin CK14, both of which are essential for the formation of 8-nm filaments. CK5 and calretinin have been useful in different studies as immunohistochemical markers suggestive of mesothelioma, and their expression is analyzed for the histological differential diagnosis with adenocarcinomas, especially when confronting with metastatic tumors of unknown origin. CK5 labels myoepithelial cells of breast and prostate basal cells. A cocktail of CK5, CK14 and p63, has been used as sensitive and specific basal cell marker of basal-like phenotype of breast carcinoma and to differentiate normal and prostate cancer. Loss-of-function mutations in the keratin 5 gene Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€464,10 Add to cart
