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KI67 antibody
Description Rabbit monoclonal KI67 antibody (Shipping Cost: €205.00) Host Rabbit Application Western Blot (WB),Immunocytochemistry (ICC),Immunohistochemistry (IHC),Immunohistochemistry on paraffin sections (IHC-P),Blocking Reactivity Dog (Canine),Human,Mouse,Pig (Porcine),Rabbit,Rat 
500 ul more info 
5-7 days 
€819,00 Add to cart -
Hemoglobin A mAb
Host Rabbit Application immunohistochemistry (formalin-fixed,Immunohistochemistry on paraffin sections (IHC-P) Reactivity Human Concentration 5-15 μg/mL
100 ul more info 5-7 days
€311,40 Add to cart -
5T4 [EPR5529]
Description 5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
Amyloid A Serum [SAA/2868R]
Description Serum Amyloid A (SAA) is an acute-phase protein primarily synthesized in the liver. While it is typically found at low concentrations in healthy individuals, pro-inflammatory cytokines upregulate SAA production to encourage recruitment of immune cells to inflammatory sites. Amyloidosis is a disease characterized by the abnormal build-up of amyloid, abnormal non-branching fibrillary β-pleated sheet proteins that are insoluble and highly resistant to proteolytic degradation that result in localized or systemic organ dysfunction. Amyloidoses are grouped as AL (primary), AA (secondary), and hereditary forms. Proper classification is important since treatment and prognoses of the disorders are vastly different. AA amyloidosis is associated with a variety of chronic inflammatory conditions and infections, derived from SAA. Immunohistochemical staining using a panel of antibodies including κ and λ Ig light chains, amyloid A, and transthyretin can aid in recognizing most forms of amyloid. Rece Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€416,00 Add to cart -
Amyloid A Serum [SAA/2868R]
Description Serum Amyloid A (SAA) is an acute-phase protein primarily synthesized in the liver. While it is typically found at low concentrations in healthy individuals, pro-inflammatory cytokines upregulate SAA production to encourage recruitment of immune cells to inflammatory sites. Amyloidosis is a disease characterized by the abnormal build-up of amyloid, abnormal non-branching fibrillary β-pleated sheet proteins that are insoluble and highly resistant to proteolytic degradation that result in localized or systemic organ dysfunction. Amyloidoses are grouped as AL (primary), AA (secondary), and hereditary forms. Proper classification is important since treatment and prognoses of the disorders are vastly different. AA amyloidosis is associated with a variety of chronic inflammatory conditions and infections, derived from SAA. Immunohistochemical staining using a panel of antibodies including κ and λ Ig light chains, amyloid A, and transthyretin can aid in recognizing most forms of amyloid. Rece Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Androgen Receptor [MD124R]
Description Androgen receptor (AR) is a member of the steroid receptor superfamily that is essential for the growth of prostate cancer cells. It has been reported that tyrosine phosphorylation of AR is induced by growth factors and elevated in hormone-refractory prostate tumors. Data suggest that growth factors and their downstream tyrosine kinases, which are elevated during hormone-ablation therapy, can induce tyrosine phosphorylation of AR . Such modification may be important for prostate tumor growth under androgen-depleted conditions. Cellular signaling occurs following androgen binding to the AR and translocation to the nucleus. This activated complex associates with androgen-responsive elements contained in the DNA sequence of target genes, affecting the transcriptional activity of these genes. AR antibody labels epithelial cells and stromal cells in normal prostate. AR reactivity is also found in other types of cells, including epithelial cells of the breast and hepatocytes. In prostate can Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€401,70 Add to cart -
Androgen Receptor [MD124R]
Description Androgen receptor (AR) is a member of the steroid receptor superfamily that is essential for the growth of prostate cancer cells. It has been reported that tyrosine phosphorylation of AR is induced by growth factors and elevated in hormone-refractory prostate tumors. Data suggest that growth factors and their downstream tyrosine kinases, which are elevated during hormone-ablation therapy, can induce tyrosine phosphorylation of AR . Such modification may be important for prostate tumor growth under androgen-depleted conditions. Cellular signaling occurs following androgen binding to the AR and translocation to the nucleus. This activated complex associates with androgen-responsive elements contained in the DNA sequence of target genes, affecting the transcriptional activity of these genes. AR antibody labels epithelial cells and stromal cells in normal prostate. AR reactivity is also found in other types of cells, including epithelial cells of the breast and hepatocytes. In prostate can Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Annexin 14/Annexin A10 [EPR19507]
Description The annexin family of calcium-binding proteins contains several family members that are characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin A10, also known as ANX14 or ANXA10, is a 324 amino acid protein that contains four Annexin domains and may be involved in the regulation of cellular growth and signal transduction pathways throughout the cell. The gene encoding Annexin A10 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€455,00 Add to cart -
Anterior Gradient 2 (AGR2) [EPR3278]
Description Anterior Gradient 2 (AGR2), also known as HAG-2 or Gob-4, is the human orthologue of the Xenopus laevis AGR protein XAG-2. In the frog embryo, XAG-2 is involved in cement gland differentiation and neural marker expression. However, the function of AGR2 in humans is unclear. AGR2 was first identified in studies focused on differentiating genes in estrogen receptor (ER)-positive breast cancers and is predominately expressed in tissues that contain mucus-secreting cells and/or function as endocrine organs. Strong AGR2 mRNA expression was found in normal human colon, stomach, rectum, prostate and breast. AGR2 has been shown to be co-expressed with ER in breast cancer cell lines and overexpression was found to attenuate p53 activation in UV-damaged cells. Immunohistochemical studies demonstrated cytoplasmic AGR2 staining in 65-83% of breast cancers. Positive staining for AGR2 in ER-positive breast cancers was significantly associated with poorer patient survival. Subsequent studies have als Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
Apolipoprotein E/ApoE [MD14R]
Description Apolipoprotein E (ApoE) is a 34.2 kDa glycosylated protein with 299 amino acid residues. There are three isoforms in human (apoE2, apoE3, and apoE4) due to different amino acid residues at positions 112 and 158. ApoE is synthesized predominantly in the liver, but also by cells in the spleen, brain, lung, kidney, ovary, adrenal, and muscle tissues. Hepatic parenchyma cells are the main apoE producing cells in mammalian body, probably accounting for two thirds to three fourths of the plasma apoE . In the nervous system, apoE mRNA is present in neurons, astrocytes, ependymal cells, nonmyelinating Schwann cells, but not in microglia, oligodendroglia, choroidal cells, or myelinating Schwann cells. ApoE produced by mammalian cells exists in different forms, monomers, dimers, modified, unmodified, lipid-rich, and lipid-poor, and so forth. ApoE plays a double-role in immune responses. Both apoE containing lipoproteins and multimers of synthetic apoE peptides inhibited proliferation of cultured Host Rabbit Application Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€442,00 Add to cart
