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  • Article number: RM0119
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    LIN28 [EP150]

    Description LIN28 is a highly conserved, RNA-binding protein (RBP). It plays an important role as a translational enhancer, leading specific mRNAs to polysomes and therefore increasing the competence of protein synthesis. LIN28 was identified as a negative regulator of miRNA biogenesis and suggested to play a central role in blocking miRNA-mediated differentiation in stem cells and certain cancers. LIN28 is expressed by various undifferentiated embryonic cell types. Anti- LIN28 has been used as a sensitive marker for germ cell tumors. The positive staining of LIN28 in yolk sac tumors showed an advantage over OCT4, which is negative in these tumors. The nuclear reactivity of this antibody maybe observed in the myoepithelial cells of the salivary gland. (Shipping Cost: €200.00)
    Host Rabbit
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €464,10 
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  • Article number: RM0119RTU7
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    LIN28 [EP150]

    Description LIN28 is a highly conserved, RNA-binding protein (RBP). It plays an important role as a translational enhancer, leading specific mRNAs to polysomes and therefore increasing the competence of protein synthesis. LIN28 was identified as a negative regulator of miRNA biogenesis and suggested to play a central role in blocking miRNA-mediated differentiation in stem cells and certain cancers. LIN28 is expressed by various undifferentiated embryonic cell types. Anti- LIN28 has been used as a sensitive marker for germ cell tumors. The positive staining of LIN28 in yolk sac tumors showed an advantage over OCT4, which is negative in these tumors. The nuclear reactivity of this antibody maybe observed in the myoepithelial cells of the salivary gland. (Shipping Cost: €200.00)
    Host Rabbit
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 7 ml
    more info
    Normal leadtime 14 days
    Calculated total €254,80 
    Add to cart
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