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OCT2 [EPR542]
Description Octamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It specifically binds to the octamer motif (5-ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 is expressed in mature B cells, predominantly germinal center B cells. Low expression of OCT-2 has been found in immature B cells, T cells and myelomonocytic cells. OCT-2 reactivity in epithelial cells and neuronal cells has also been reported. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas. In a study on Hodgkin's lymphoma (HL), OCT-2 positivity has been observed in 15 out of 15 lymphocyte predominance HLs, but none of the 29 classic HLs. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 
14 days 
€494,00 Add to cart -
OCT2 [EPR542]
Description Octamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It specifically binds to the octamer motif (5-ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 is expressed in mature B cells, predominantly germinal center B cells. Low expression of OCT-2 has been found in immature B cells, T cells and myelomonocytic cells. OCT-2 reactivity in epithelial cells and neuronal cells has also been reported. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas. In a study on Hodgkin's lymphoma (HL), OCT-2 positivity has been observed in 15 out of 15 lymphocyte predominance HLs, but none of the 29 classic HLs. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart
