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  • Article number: RM0244
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    BRAF V600E [MD58R]

    Description Serine/threonine-protein kinase B-raf (BRAF) is a member of the Raf family. BRAF mutations are frequent in benign and malignant human tumors. BRAF V600E mutation accounts for the vast majority of BRAF alterations and the mutation induces a conformational change of the activation segment leading to a constitutive kinase activity of BRAF and consecutive phosphorylation of downstream targets. BRAF V600E mutation have been detected in melanoma, papillary thyroid carcinoma, pleomorphic xanthoastrocytomas, Langerhans cell histiocytosis, borderline ovarian cancer, ganglioglioma, colorectal carcinoma, and pilocytic astrocytoma. (Shipping Cost: €200.00)
    Host Rabbit
    Application ELISA, Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blot (WB)
    Reactivity Human
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €508,30 
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