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  • Article number: 10R-C144b
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    COX2 antibody

    Description Rabbit monoclonal COX2 antibody (Shipping Cost: €205.00)
    Host Rabbit
    Application Immunohistochemistry on frozen sections (IHC-Fs),Immunohistochemistry on paraffin sections (IHC-P)
    Concentration Batch dependent - please inquire should you have specific requirements
    Specificity Human
    Unit 500 ul
    more info
    Normal leadtime 5-7 days
    Calculated total €0,01 
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  • Article number: RM0200
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    COX2 [MD144R]

    Description COX-2, also known as prostaglandin-endoperoxidase synthase 2 (PTGS2), is an immediate-early gene that encodes a critical enzyme for the conversion of arachidonic acids to prostaglandins. Functionally, COX-2 exists as a homodimer, consisting of two 70kDa subunits. COX-2 derived prostanoids have been shown to increase resistance to apoptosis, promote angiogenesis, induce metastasis and invasion, and impair immune surveillance. Immunohistochemical expression of COX-2 has been described in multiple tissue types. While COX-2 expression is limited in most normal tissues, it is induced by various stimuli and elevated during inflammatory responses. Reports have associated COX-2 expression with cancers from multiple tissues. Lung, colon, gastric, prostate, and breast carcinomas were described to have elevated levels of COX-2. Further, elevated COX-2 levels has been associated with poor prognosis and decreased survival in patients with breast cancer. (Shipping Cost: €200.00)
    Host Rabbit
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €401,70 
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  • Article number: RM0200RTU7
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    COX2 [MD144R]

    Description COX-2, also known as prostaglandin-endoperoxidase synthase 2 (PTGS2), is an immediate-early gene that encodes a critical enzyme for the conversion of arachidonic acids to prostaglandins. Functionally, COX-2 exists as a homodimer, consisting of two 70kDa subunits. COX-2 derived prostanoids have been shown to increase resistance to apoptosis, promote angiogenesis, induce metastasis and invasion, and impair immune surveillance. Immunohistochemical expression of COX-2 has been described in multiple tissue types. While COX-2 expression is limited in most normal tissues, it is induced by various stimuli and elevated during inflammatory responses. Reports have associated COX-2 expression with cancers from multiple tissues. Lung, colon, gastric, prostate, and breast carcinomas were described to have elevated levels of COX-2. Further, elevated COX-2 levels has been associated with poor prognosis and decreased survival in patients with breast cancer. (Shipping Cost: €200.00)
    Host Rabbit
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 7 ml
    more info
    Normal leadtime 14 days
    Calculated total €214,50 
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