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SMAD3 antibody
Description Mouse monoclonal SMAD3 antibody (Shipping Cost: €205.00) Host Mouse Application ELISA,Immunofluorescence (IF),Western Blot (WB) Reactivity Human,Mouse Concentration 1.0 mg/ml -
Purified anti-mouse lymphotoxin beta receptor (LTβR)
Description Purified anti-mouse lymphotoxin beta receptor (LTβR) 5G11 100 µg (Shipping Cost: €40.00) Host Rat Reactivity Mouse Concentration 0.5 mg/ml Specificity LTbR -
PE anti-mouse lymphotoxin beta receptor (LTβR)
Description PE anti-mouse lymphotoxin beta receptor (LTβR) 5G11 25 µg (Shipping Cost: €40.00) Host Rat Reactivity Mouse Concentration 0.2 mg/ml Conjugate Phycoerythrin (PE) Specificity LTbR -
APC anti-mouse lymphotoxin beta receptor (LTβR)
Host Rat Reactivity Mouse Concentration 0.2 mg/ml Conjugate Allophycocyanin (APC) -
APC anti-mouse lymphotoxin beta receptor (LTβR)
Host Rat Reactivity Mouse Concentration 0.2 mg/ml Conjugate Allophycocyanin (APC) -
PE/Cy7 anti-mouse lymphotoxin beta receptor (LTβR)
Host Rat Reactivity Mouse Concentration 0.2 mg/ml Conjugate PE/Cy7™ tandem -
PE/Cy7 anti-mouse lymphotoxin beta receptor (LTβR)
Host Rat Reactivity Mouse Concentration 0.2 mg/ml Conjugate PE/Cy7™ tandem -
Desmoglein-3 [5G11]
Description Desmoglein-3 (DSG3) is a calcium binding membrane protein that is localized desmosome cellular junctions and interacts with plaque proteins and intermediate filaments at cell-cell adhesion points. Desmosomes are cell-cell junctions between epithelial, myocardial and other cells types. In human keratinocytes, Desmoglein-3 (DSG3) is raft associated and disruption of rafts prevents desmosome assembly. DSG3 is one of four sister proteins in the desmoglein family. DSG3 is also the autoantigen for pemphigus vulgaris (PV) a lethal skin disease that is a result of autoantibodies against DSG3. DSG3 is over-expressed in lung squamous cell carcinomas (SQCC) but had very limited expression in both adenocarcinomas and non-neoplastic lungs. Using immunohistochemistry, the sensitivity and specificity of DSG3 for lung cancers were 98% and 99%, respectively, which is similar to that of p40. Therefore, DSG3 can be a useful ancillary marker to separate SQCC from other subtypes of lung cancer. (Shipping C Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human -
Desmoglein-3 [5G11]
Description Desmoglein-3 (DSG3) is a calcium binding membrane protein that is localized desmosome cellular junctions and interacts with plaque proteins and intermediate filaments at cell-cell adhesion points. Desmosomes are cell-cell junctions between epithelial, myocardial and other cells types. In human keratinocytes, Desmoglein-3 (DSG3) is raft associated and disruption of rafts prevents desmosome assembly. DSG3 is one of four sister proteins in the desmoglein family. DSG3 is also the autoantigen for pemphigus vulgaris (PV) a lethal skin disease that is a result of autoantibodies against DSG3. DSG3 is over-expressed in lung squamous cell carcinomas (SQCC) but had very limited expression in both adenocarcinomas and non-neoplastic lungs. Using immunohistochemistry, the sensitivity and specificity of DSG3 for lung cancers were 98% and 99%, respectively, which is similar to that of p40. Therefore, DSG3 can be a useful ancillary marker to separate SQCC from other subtypes of lung cancer. (Shipping C Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human