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Article number: MC0792RTU7

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Glypican-3 [GPC3/863]

Description	Glypican-3 (GPC3) is a member of the glypican family of glycosyl phosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans. GPC3 is a tissue and serum biomarker for the early detection of hepatocellular carcinoma. The anti-GPC3 antibody has been used to assess GPC3 expression in malignant and non-malignant liver tissue samples and for quantitative ELISA detection of GPC3 concentration in the serum. Capurro et al. have shown that GPC3 is expressed at the protein level by immunohistochemistry in most cases of primary liver cancer including small tumors, but is undetectable in normal liver and benign hepatic lesions. In addition, the authors found that GPC3 is significantly elevated in the serum of a large proportion of patients with Primary Liver Cancer. (Shipping Cost: €200.00)
Host	Mouse
Application	Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC)
Reactivity	Human, Rat

Article number: MC0347

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Description	TDP43 or TAR DNA-binding protein 43 belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. It is also is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in TDP43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease. (Shipping Cost: €200.00)
Host	Mouse
Application	Immunohistochemistry (IHC), Western Blot (WB)
Reactivity	Human, Mouse, Rat

Article number: MF012M

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Description	MedaFluo™ 550 Mouse on Rat Immunofluorescence Detection Kit (Shipping Cost: €200.00)
Host	Mouse
Reactivity	Rat

Article number: MF012S

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Description	MedaFluo™ 550 Mouse on Rat Immunofluorescence Detection Kit (Shipping Cost: €200.00)
Host	Mouse
Reactivity	Rat

Article number: MF013M

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Description	MedaFluo™ 594 Mouse on Rat Immunofluorescence Detection Kit (Shipping Cost: €200.00)
Host	Mouse
Reactivity	Rat

Article number: MF013S

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Description	MedaFluo™ 594 Mouse on Rat Immunofluorescence Detection Kit (Shipping Cost: €200.00)
Host	Mouse
Reactivity	Rat

Article number: MF014M

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Description	MedaFluo™ 650 Mouse on Rat Immunofluorescence Detection Kit (Shipping Cost: €200.00)
Host	Mouse
Reactivity	Rat

Article number: MF014S

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Description	MedaFluo™ 650 Mouse on Rat Immunofluorescence Detection Kit (Shipping Cost: €200.00)
Host	Mouse
Reactivity	Rat

Article number: RC0001

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Description	CD69 is also known as activation-induced molecule (AIM), early activation antigen (EA-1), very early activation antigen (VEA), C-type lectin domain family 2 member C (CLEC2C), MLR-3, GP32/28 and Leu-23. CD69 is a transmembrane type II homodimer receptor. CD69 is comprised of disulfide-linked, differentially glycosylated core protein subunits that are approximately 28 and 34 kDa in size. Each subunit contains a C-type lectin domain. CD69 is expressed on activated T, B, and natural killer (NK) lymphocytes, thymocytes, neutrophils, eosinophils and platelets. In normal peripheral blood, a small and variable percentage of lymphocytes typically express detectable membrane CD69 antigen. Upon activation, CD69 antigen expression increases on lymphocytes. Peak CD69 expression generally occurs within 18 hours of activation, preceding the appearance of HLA-DR, IL-2Rα (CD25) and transferrin receptor (CD71). CD69 is highly expressed on the bright CD3+ subset of thymocytes. FN50 monoclonal antibody l
Host	Rabbit
Application	ELISA, Immunohistochemistry (IHC), Western Blot (WB)
Reactivity	Human, Mouse, Rat, Dog

Article number: RC0001RTU7

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Description	CD69 is also known as activation-induced molecule (AIM), early activation antigen (EA-1), very early activation antigen (VEA), C-type lectin domain family 2 member C (CLEC2C), MLR-3, GP32/28 and Leu-23. CD69 is a transmembrane type II homodimer receptor. CD69 is comprised of disulfide-linked, differentially glycosylated core protein subunits that are approximately 28 and 34 kDa in size. Each subunit contains a C-type lectin domain. CD69 is expressed on activated T, B, and natural killer (NK) lymphocytes, thymocytes, neutrophils, eosinophils and platelets. In normal peripheral blood, a small and variable percentage of lymphocytes typically express detectable membrane CD69 antigen. Upon activation, CD69 antigen expression increases on lymphocytes. Peak CD69 expression generally occurs within 18 hours of activation, preceding the appearance of HLA-DR, IL-2Rα (CD25) and transferrin receptor (CD71). CD69 is highly expressed on the bright CD3+ subset of thymocytes. FN50 monoclonal antibody l
Host	Rabbit
Application	ELISA, Immunohistochemistry (IHC), Western Blot (WB)
Reactivity	Human, Mouse, Rat, Dog