You are here
-
Cytokeratin Cocktail [AE1&AE3]
Description The antibody cocktail labels simple epithelia and their tumors including cytokeratins expressed in complex stratified squamous epithelia. Positive results aid in the classification of normal and a wide range of neoplastic tissues as epithelial in origin. This antibody serves as first tier antibody for differentiation of undifferentiated neoplasm. Pan Cytokeratin clone AE1/AE3 antibody may be used with a panel of antibodies for differential diagnosis, e.g. Breast vs. lung or liver: CK7, AE1/AE3, CEA, GCDFP-15, TTF-1; Renal vs. lung or liver: AE1/AE3, CEA, TTF-1, Renal Cell Ag; Seminoma vs. lung or liver: CAM5.2, AE1/AE3, PLAP, EMA, CD30; Embryonal germ cell vs. lung or liver: AE1/AE3, TTF-1, CK7, PLAP, CD30. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), (0.5-1ug/million cells), Immunocytochemistry (ICC)/IF (1-2ug/ml), Immunohistochemistry (IHC), Western Blot (WB) (0.5-1ug/ml 2 hrs RT) Reactivity Human, Mouse, Rat, Rabbit, Monkey, Bovine, Dog (Canine), Chicken -
Cytokeratin, pan [PAN-CK (Cocktail)]
Description Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1, CK2, CK3, CK4, CK5, CK6, CK7, CK8 and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10, CK12, CK 13, CK14, CK16, CK17, CK18, CK19 and CK20.This antibody recognizes low molecular weight cytokeratins (CK 10 (56.5), CK14 (50), CK15 (50), CK16 (48) and CK19(40) of the acidic family. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Bovine, Dog (Canine), Rabbit, Mouse, Rat, Chicken -
Cytokeratin, pan [PAN-CK (Cocktail)]
Description Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1, CK2, CK3, CK4, CK5, CK6, CK7, CK8 and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10, CK12, CK 13, CK14, CK16, CK17, CK18, CK19 and CK20.This antibody recognizes low molecular weight cytokeratins (CK 10 (56.5), CK14 (50), CK15 (50), CK16 (48) and CK19(40) of the acidic family. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Bovine, Dog (Canine), Rabbit, Mouse, Rat, Chicken -
GFAP [GA-5]
Description Glial fibrillary acidic protein (GFAP) is the subunit of the glial specific “intermediate” filament that include desmin filaments in smooth muscle, vimentin filaments in cultured fibroblasts, keratin filaments in epithelium and neurofilaments in neural cells. GFAP is a major product of astrocytic differentiation. Compared with special stains currently used to identify an astroglial component in brain tumors, GFAP staining is more sensitive. Further, the immunohistochemical staining method is useful in demonstrating reactive astrocytes, whether secondary to a brain tumor or to any other neuro-pathological condition. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Western Blot (WB) Reactivity Human, Mouse, Rat, Rabbit, Chicken, Bovine,Pig (Porcine) -
GFAP [GA-5]
Description Glial fibrillary acidic protein (GFAP) is the subunit of the glial specific “intermediate” filament that include desmin filaments in smooth muscle, vimentin filaments in cultured fibroblasts, keratin filaments in epithelium and neurofilaments in neural cells. GFAP is a major product of astrocytic differentiation. Compared with special stains currently used to identify an astroglial component in brain tumors, GFAP staining is more sensitive. Further, the immunohistochemical staining method is useful in demonstrating reactive astrocytes, whether secondary to a brain tumor or to any other neuro-pathological condition. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Western Blot (WB) Reactivity Human, Mouse, Rat, Rabbit, Chicken, Bovine,Pig (Porcine) -
Heat Shock Protein (HSP60) (Mitochondrial Marker) [LK1]
Description Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone LK1, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat, Hamster, Sheep, Rabbit, Bovine, Dog (Canine),Pig (Porcine), Monkey, Chicken, Xenopus laevis, Drosophila -
Insulin [E2-E3]
Description Insulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. It is synthesized in the beta cell of the pancreas. The antibody labels both normal and neoplastic insulin-producing cells. It is useful in identifying insulinoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rabbit, Bovine,Pig (Porcine) -
Insulin [E2-E3]
Description Insulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. It is synthesized in the beta cell of the pancreas. The antibody labels both normal and neoplastic insulin-producing cells. It is useful in identifying insulinoma. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human, Mouse, Rabbit, Bovine,Pig (Porcine) -
Internexin Alpha/NF66 [2E3]
Description Alpha–internexin is an intermediate filament family member expressed during early neuron development and is related to the neurofilament proteins NF-H, NF-L and NF-M. Due to the specific spatial and temporal expression pattern of alpha-internexin, it is a useful marker of neuronal subtypes. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. It is expressed in large amounts early in neuronal development, but is downregulated in many neurons as development proceeds. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to a-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. The very early developmental expression of alpha-internexin means its pr Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rat, Mouse, Cat, Rabbit, Bovine, Pig -
Internexin Alpha/NF66 [2E3]
Description Alpha–internexin is an intermediate filament family member expressed during early neuron development and is related to the neurofilament proteins NF-H, NF-L and NF-M. Due to the specific spatial and temporal expression pattern of alpha-internexin, it is a useful marker of neuronal subtypes. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. It is expressed in large amounts early in neuronal development, but is downregulated in many neurons as development proceeds. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to a-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. The very early developmental expression of alpha-internexin means its pr Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rat, Mouse, Cat, Rabbit, Bovine, Pig