Search

Article number: RC0329

Add to compare

CD64/IGFR1 Polyclonal

Description	This antibody recognizes CD64 also known as FcRI. CD64 is a high affinity activatory receptor for IgG2a and a low affinity receptor for IgG2b and IgG3 type antibodies. The interaction between Fc receptors and antibodies play important roles in both the innate and adaptive immune responses. CD64 through binding of the Fc segment of IgG, mediates phagocytosis and plays a role in antibody-dependent cellular cytotoxicity and clearance of immune complexes. In addition, CD64 also functions as an antigen capture for presentation to T-cells and also mediates the release of cytokines and reactive oxygen intermediates including interleukin (IL)-1, IL-6 and tumor necrosis factor (TNF) alpha. It is constitutively expressed on monocytes and macrophages, germinal centre dendritic cells and early myeloid lineage cells, but not lymphocytes. Expression on monocytes can be strongly upregulated by treatment with interferon (IFN) gamma or G-CSF, and can be induced on neutrophils and eosinophils by IFN gam
Host	Rabbit
Application	ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Reactivity	Human, Mouse, Rat

Article number: RC0329RTU7

Add to compare

Description	This antibody recognizes CD64 also known as FcRI. CD64 is a high affinity activatory receptor for IgG2a and a low affinity receptor for IgG2b and IgG3 type antibodies. The interaction between Fc receptors and antibodies play important roles in both the innate and adaptive immune responses. CD64 through binding of the Fc segment of IgG, mediates phagocytosis and plays a role in antibody-dependent cellular cytotoxicity and clearance of immune complexes. In addition, CD64 also functions as an antigen capture for presentation to T-cells and also mediates the release of cytokines and reactive oxygen intermediates including interleukin (IL)-1, IL-6 and tumor necrosis factor (TNF) alpha. It is constitutively expressed on monocytes and macrophages, germinal centre dendritic cells and early myeloid lineage cells, but not lymphocytes. Expression on monocytes can be strongly upregulated by treatment with interferon (IFN) gamma or G-CSF, and can be induced on neutrophils and eosinophils by IFN gam
Host	Rabbit
Application	ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Reactivity	Human, Mouse, Rat

Article number: MF041M

Add to compare

Description	MedaFluo™ 488 Immunofluorescence Rabbit Detection Kit (Shipping Cost: €200.00)
Host	Rabbit
Reactivity	Human, Mouse, Goat

Article number: MF041S

Add to compare

Description	MedaFluo™ 488 Immunofluorescence Rabbit Detection Kit (Shipping Cost: €200.00)
Host	Rabbit
Reactivity	Human, Mouse, Goat

Article number: MF042M

Add to compare

Description	MedaFluo™ 550 Immunofluorescence Rabbit Detection Kit (Shipping Cost: €200.00)
Host	Rabbit
Reactivity	Human, Mouse, Goat

Article number: MF042S

Add to compare

Description	MedaFluo™ 550 Immunofluorescence Rabbit Detection Kit (Shipping Cost: €200.00)
Host	Rabbit
Reactivity	Human, Mouse, Goat

Article number: MF043M

Add to compare

Description	MedaFluo™ 594 Immunofluorescence Rabbit Detection Kit (Shipping Cost: €200.00)
Host	Rabbit
Reactivity	Human, Mouse, Goat

Article number: MF043S

Add to compare

Description	MedaFluo™ 594 Immunofluorescence Rabbit Detection Kit (Shipping Cost: €200.00)
Host	Rabbit
Reactivity	Human, Mouse, Goat

Article number: MF044M

Add to compare

Description	MedaFluo™ 650 Immunofluorescence Rabbit Detection Kit (Shipping Cost: €200.00)
Host	Rabbit
Reactivity	Human, Mouse, Goat

Article number: MF044S

Add to compare

Description	MedaFluo™ 650 Immunofluorescence Rabbit Detection Kit (Shipping Cost: €200.00)
Host	Rabbit
Reactivity	Human, Mouse, Goat