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  • Article number: RM0068
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    Claudin 5 [EPR7583]

    Description Claudin 5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction (TJ) strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Claudin 5 is an endothelial cell-specific component of TJ strands. Mutations in Claudin 5 have been found in patients with velocardiofacial syndrome. Claudin 5 labels endothelial cells. It has been used as a marker for endothelial lesions. Claudin 5 is also found in bronchial and lung epithelial cells. In tumors, Claudin 5 expression has been found in lung adenocarcinoma and squamous carcinoma. In serous ovarian adenocarcinoma, increased Claudin-5 expression is associated with aggressive behavior. (Shipping Cost: €200.00)
    Host Rabbit
    Application Immunohistochemistry (IHC), Western Blot (WB)
    Reactivity Human, Mouse
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €464,10 
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  • Article number: RM0068RTU7
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    Claudin 5 [EPR7583]

    Description Claudin 5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction (TJ) strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Claudin 5 is an endothelial cell-specific component of TJ strands. Mutations in Claudin 5 have been found in patients with velocardiofacial syndrome. Claudin 5 labels endothelial cells. It has been used as a marker for endothelial lesions. Claudin 5 is also found in bronchial and lung epithelial cells. In tumors, Claudin 5 expression has been found in lung adenocarcinoma and squamous carcinoma. In serous ovarian adenocarcinoma, increased Claudin-5 expression is associated with aggressive behavior. (Shipping Cost: €200.00)
    Host Rabbit
    Application Immunohistochemistry (IHC), Western Blot (WB)
    Reactivity Human, Mouse
    Unit 7 ml
    more info
    Normal leadtime 14 days
    Calculated total €254,80 
    Add to cart
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