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MVH/DDX4/VASA [2F9H5]
Description MVH or DDX4 or VASA is a 724 amino acid, ATP-dependent RNA helicase that belongs to the DEAD-box family. MVH is specifically expressed in germline cells throughout the life cycle and is undetectable in somatic tissues. In vertebrates, MVH is restricted to bisexually reproducing organisms. It is cytoplasmic and is present only in migratory primordial germ cells in the region of the gonadal ridge. On testicular sections, MVH expression is the highest in spermatogonia, reduced in spermatocytes, low in spermatids and absent in sperm. In the ovary, MVH expression is the highest in oogonia but persists throughout oogenesis. MVH has a glycine-rich N-terminus with multiple repeats of an RGG motif believed to function in RNA binding. Specifically, it regulates the translation of intricate mRNAs that are essential for differentiation. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB), Reactivity Human 
1 ml more info 
14 days 
€361,40 Add to cart -
MxA/MX1/IFI78K [M143]
Description Interferon-induced GTP-binding protein Mx1 (UniProt P20591; also known as IFI-78K, Interferon-induced protein p78, Interferon-inducible protein p78, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance 1) is encoded by the MX1 (also known as MX, IFI78) gene (Gene ID 4599) in human. The interferon-inducible myxovirus resistance (Mx) proteins belong to the family of large GTPases and are highly homologous with dynamins within their GTP-binding domain. Mx proteins differ from small GTPases and heterotrimeric G proteins in features such as their large size (70–100 kDa), a relatively low affinity for GTP, and a high intrinsic rate of GTP hydrolysis. Mx proteins contain a highly conserved tripartite GTP-binding motif within the N-terminal G domain, while their less conserved C-terminal half serves different functions such as homooligomerization and association with binding partners. Two distinct regions of human MxA, a central interactive Host Mouse Application Flow cytometry (FC), Immunohistochemistry (IHC), Western Blot (WB), Reactivity Human, Mouse, Rat, Guinea Pig
1 ml more info 14 days
€546,00 Add to cart -
Myeloid Associated Differentiation Marker [MYADM/972]
Description Recognizes a myeloid associated differentiation antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of human and monkey myeloid cells. This MAb is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Macaque
1 ml more info 14 days
€361,40 Add to cart -
Myeloid Associated Differentiation Marker [MYADM/972]
Description Recognizes a myeloid associated differentiation antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of human and monkey myeloid cells. This MAb is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Macaque
7 ml more info 14 days
€187,20 Add to cart -
Myeloid Cell (Macrophage / Granulocyte Marker) [BM-1]
Description This antibody reacts with an antigen present in the cytoplasm of mature human granulocytes. It reacts with the precursor and mature forms of human myeloid cells. This antibody can be used to detect myeloid leukemias and granulocytic sarcomas as well as different levels of cellular differentiation. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Myeloid Cell Marker (Macrophage / Granulocyte Marker) [BM-1]
Description This antibody reacts with an antigen present in the cytoplasm of mature human granulocytes. It reacts with the precursor and mature forms of human myeloid cells. This antibody can be used to detect myeloid leukemias and granulocytic sarcomas as well as different levels of cellular differentiation. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
MyoD1 (Rhabdomyosarcoma Marker) [5.8A]
Description Recognizes a phosphor-protein of 45kDa, identified as MyoD1. The epitope of this antibody maps between amino acid 180-189 in the C-terminal of mouse MyoD1 protein. It does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat, Chicken
1 ml more info 14 days
€361,40 Add to cart -
Myogenin (MyF4) [F5D]
Description Myogenic factors are transcription factors consisting of an amino acid-rich region and a helix-loop-helix (HLH) structure, which can promote muscle development and maintain muscle-specific gene expression by transactivation. Myogenin, one of the myogenic regulatory factors, plays a key role in determining the commitment and differentiation of primitive mesenchymal cells into skeletal muscle. The expression of Myogenin is restricted to cells of skeletal muscle origin, but it is not detected in adult skeletal muscles. It is therefore considered to be an extremely reliable and specific marker for diagnosing rhabdomyosarcomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Myogenin (MyF4) [F5D]
Description Myogenic factors are transcription factors consisting of an amino acid-rich region and a helix-loop-helix (HLH) structure, which can promote muscle development and maintain muscle-specific gene expression by transactivation. Myogenin, one of the myogenic regulatory factors, plays a key role in determining the commitment and differentiation of primitive mesenchymal cells into skeletal muscle. The expression of Myogenin is restricted to cells of skeletal muscle origin, but it is not detected in adult skeletal muscles. It is therefore considered to be an extremely reliable and specific marker for diagnosing rhabdomyosarcomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€234,00 Add to cart -
Myoglobin [MB/2105]
Description Myoglobin, an intracellular haemoprotein expressed in the heart and oxidative skeletal myofibres of vertebrates, binds molecular oxygen and may facilitate oxygen transport from erythrocytes to mitochondria, thereby maintaining cellular respiration during periods of high physiological demand. Antibody to myoglobin labels skeletal and cardiac muscle cells. In combination with other striated muscle markers such as vimentin and myogenin, myoglobin is helpful in identification of rhabdomyosarcoma and tumors with skeletal muscle differentiation. Recently, myoglobin has been reported to be expressed on epithelial cancer cells due to changed metabolic and environmental conditions. Myoglobin expression on cancer cells may play a causative role in tumor progression. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€374,40 Add to cart
