You are here
-
Metapneumovirus Nucleoprotein (MPV NP) [hMPV57]
Description Metapneumovirus is a discovered paramyxovirus of the subfamily Pneumovirinae, which also includes avian pneumovirus and human respiratory syncytial virus (HRSV). Human metapneumovirus (HMPV) is classified as a member of the family Pneumoviridae, which comprises large enveloped negative-sense RNA viruses. This taxon was formerly a subfamily within the Paramyxoviridae family but was reclassified in 2016 as a separate family with two genera, Metapneumovirus (which includes HMPV) and Orthopneumovirus (which includes respiratory syncytial virus). HMPV is an enveloped virus with a nonsegmented negative-sense RNA genome. HMPV is most closely related phylogenetically to avian metapneumovirus (APV). The complete genome sequence reveals a high level of homology with APV. Phylogenetic analysis has identified two subgroups of HMPV, subgroups A and B, and two clades within each of these subgroups (designated A1, A2, B1, and B2), which often circulate concurrently. A study of 727 Australian HMPV iso Host Mouse Application Immunohistochemistry (IHC), ICC Reactivity Human