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CD5 [C5/473&CD5/54/F6]
Description CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation. CD5 antibody labels a variety of T lymphocytes, mantle zone lymphocytes and a small subset of B lymphocytes. In tumors, CD5 is expressed on T-cell malignancies, Bcell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), and mantle-cell lymphoma. It is a useful diagnostic tool for these tumors. In addition, anti-CD5 is helpful in diagnosis of thymic carcinoma (CD5 positive). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rabbit, Rat, Bovine 
7 ml more info 
14 days 
€187,20 Add to cart -
Collagen I [COL1]
Description The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. This clone reacts collagen I. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Bovine,Pig (Porcine), Cat, Dog
1 ml more info 14 days
€401,70 Add to cart -
Collagen I [COL1]
Description The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. This clone reacts collagen I. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat, Bovine,Pig (Porcine), Cat, Dog
7 ml more info 14 days
€187,20 Add to cart -
Connexin 43/GJA1 [F7]
Description The connexins are a group of gap junction proteins which form a hexamer to compose a connexon. Clusters of connexons form a gap junction through which low molecular weight proteins may diffuse from cell to cell. Several mammalian cells with malignant phenotypes exhibit decreased connexin expression and gap junction communication. In Src transformed cells, there is a decrease in gap junctional communication, which appears to be associated with tyrosine phosphorylation of connexin 43. Activated c-Src phosphorylates the C-terminal tail of connexin 43 on Tyr 265, resulting in a stable interaction between both proteins, which leads to inhibition of gap junctional communication. In addition to tyrosine phosphorylation, connexin 43 has also been shown to be phosphorylated on serine in the absence of Src kinases and on both serine and tyrosine in cells expressing Src kinases, such as c-Src and/or pp60v-Src. In human vascular endothelial cells, connexin 43 is posttranslationally modified during Host Mouse Application Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat, Bovine
1 ml more info 14 days
€361,40 Add to cart -
Connexin 43/GJA1 [F7]
Description The connexins are a group of gap junction proteins which form a hexamer to compose a connexon. Clusters of connexons form a gap junction through which low molecular weight proteins may diffuse from cell to cell. Several mammalian cells with malignant phenotypes exhibit decreased connexin expression and gap junction communication. In Src transformed cells, there is a decrease in gap junctional communication, which appears to be associated with tyrosine phosphorylation of connexin 43. Activated c-Src phosphorylates the C-terminal tail of connexin 43 on Tyr 265, resulting in a stable interaction between both proteins, which leads to inhibition of gap junctional communication. In addition to tyrosine phosphorylation, connexin 43 has also been shown to be phosphorylated on serine in the absence of Src kinases and on both serine and tyrosine in cells expressing Src kinases, such as c-Src and/or pp60v-Src. In human vascular endothelial cells, connexin 43 is posttranslationally modified during Host Mouse Application Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat, Bovine
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin [C11]
Description Monoclonal Anti-Pan Cytokeratin (clone C-11) recognizes human cytokeratins 4, 5, 6, 8, 10, 13 and 18. The antibody reacts with simple, cornifying and non-cornifying squamous epithelia and pseudostratified epithelia. It does not react with non-epithelial normal human tissues. This antibody can be applied to methanol or acetone-fixed, frozen sections, and to formalin-fixed, paraffin-embedded human tissues. Increased staining intensity is seen following proteolytic treatment of formalin fixed tissue. Similarly, methacarn-fixed material is also suitable for cytokeratin demonstration. Monoclonal Anti-Pan cytokeratin exhibits a wide interspecies cross-reactivity (e.g., human, bovine, rat, frog). Monoclonal anti-cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Mouse monoclonal clone C-11 anti-cytokeratin, pan antibody is a broad spectrum antibody which recognizes an epitope present in most human Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Bovine, Rat, Mouse, Guinea Pig, Frog, Goat, Marmoset,Pig (Porcine)
1 ml more info 14 days
€361,40 Add to cart -
Cytokeratin [C11]
Description Monoclonal Anti-Pan Cytokeratin (clone C-11) recognizes human cytokeratins 4, 5, 6, 8, 10, 13 and 18. The antibody reacts with simple, cornifying and non-cornifying squamous epithelia and pseudostratified epithelia. It does not react with non-epithelial normal human tissues. This antibody can be applied to methanol or acetone-fixed, frozen sections, and to formalin-fixed, paraffin-embedded human tissues. Increased staining intensity is seen following proteolytic treatment of formalin fixed tissue. Similarly, methacarn-fixed material is also suitable for cytokeratin demonstration. Monoclonal Anti-Pan cytokeratin exhibits a wide interspecies cross-reactivity (e.g., human, bovine, rat, frog). Monoclonal anti-cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Mouse monoclonal clone C-11 anti-cytokeratin, pan antibody is a broad spectrum antibody which recognizes an epitope present in most human Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Bovine, Rat, Mouse, Guinea Pig, Frog, Goat, Marmoset,Pig (Porcine)
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin 17 [E3]
Description CK17 is an intermediate filament protein expressed in the basal cells and myoepithelial cells of complex epithelia, including glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. CK17 is a marker in the identification of breast cancer with basal phenotype. Squamous cell carcinoma is also labeled by CK17 antibody. Antibody against CK17 may be an aid in distinguishing cholangiocarcinoma (CK17+) from hepatocellular carcinoma (CK17-). In combination with MUC1, CK17 antibody has been found to be useful in distinguishing pancreatobiliary adenocarcinoma (CK17+) from extrapancreatobiliary nonmucinous adenocarcinoma (CK17-). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rat, Bovine, Goat,Pig (Porcine)
1 ml more info 14 days
€361,40 Add to cart -
Cytokeratin 17 [E3]
Description CK17 is an intermediate filament protein expressed in the basal cells and myoepithelial cells of complex epithelia, including glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. CK17 is a marker in the identification of breast cancer with basal phenotype. Squamous cell carcinoma is also labeled by CK17 antibody. Antibody against CK17 may be an aid in distinguishing cholangiocarcinoma (CK17+) from hepatocellular carcinoma (CK17-). In combination with MUC1, CK17 antibody has been found to be useful in distinguishing pancreatobiliary adenocarcinoma (CK17+) from extrapancreatobiliary nonmucinous adenocarcinoma (CK17-). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Rat, Bovine, Goat,Pig (Porcine)
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin 5/8 [C-50]
Description It reacts with keratin 5 (58kDa) and keratin 8 (52.5kDa). Simple epithelia express cytokeratin 8 in combination with 18. On the other hand, basal cells of stratified epithelia express cytokeratin 5 paired with 14. This antibody therefore, reacts with a wide range of epithelia and their carcinomas. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human,Pig (Porcine), Mouse, Rat, Hamster, Bovine, Dog (Canine), Sheep
1 ml more info 14 days
€361,40 Add to cart
