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CD44 (HCAM) [156-3C11]
Description CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including cell-to-cell and cell-to-matrix adhesion, lymphocyte homing and tumor cell metastasis. Several isoforms of CD44 have been identified in human cells, and the genesis of some of these isoforms has been attributed to alternative splicing. Understanding of mechanisms regulating CD44 alternative splicing may provide insights into diverse processes, including tumor-cell metastasis and lymphocyte homing. CD44 is widely expressed on many types of cells with mesodermal and hematopoietic origin, epithelial cells and a variety of tumors derived from these cells. Loss of CD44 expression has been linked to tumor invasion, metastasis and progression in carcinomas of breast, prostate, lung, ovary and malignant melanoma. Expressed on approximately 90% of lymphocytes, monocytes, granulocytes, and, in lower amounts on thymocytes, fibroblasts, and erythrocytes. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, African green Monkey (Chlorocebus) 
1 ml more info 
14 days 
€361,40 Add to cart -
CD44 (HCAM) [156-3C11]
Description CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including cell-to-cell and cell-to-matrix adhesion, lymphocyte homing and tumor cell metastasis. Several isoforms of CD44 have been identified in human cells, and the genesis of some of these isoforms has been attributed to alternative splicing. Understanding of mechanisms regulating CD44 alternative splicing may provide insights into diverse processes, including tumor-cell metastasis and lymphocyte homing. CD44 is widely expressed on many types of cells with mesodermal and hematopoietic origin, epithelial cells and a variety of tumors derived from these cells. Loss of CD44 expression has been linked to tumor invasion, metastasis and progression in carcinomas of breast, prostate, lung, ovary and malignant melanoma. Expressed on approximately 90% of lymphocytes, monocytes, granulocytes, and, in lower amounts on thymocytes, fibroblasts, and erythrocytes. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, African green Monkey (Chlorocebus)
7 ml more info 14 days
€187,20 Add to cart -
CD74 [LN-2]
Description Cluster of Differentiation 74 (CD74) is a type II transmembrane protein. In normal tissues, CD74 is expressed in B cells, monocytes, macrophages, Langerhans cells, dendritic cells, subsets of activated T cells, and thymic epithelium. Under inflammatory conditions, CD74 expression may be observed in endothelial and certain epithelial cells. CD74 expression has been observed in ~90% of B-cell cancers evaluated, as well as the majority of cell lines derived from these cancers.CD74 is a marker for distinguishing atypical fibroxanthoma from malignant fibrous histiocytoma, and it is also a useful marker for distinguishing leiomyosarcoma from leiomyoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, Mouse
1 ml more info 14 days
€361,40 Add to cart -
CD74 [LN-2]
Description Cluster of Differentiation 74 (CD74) is a type II transmembrane protein. In normal tissues, CD74 is expressed in B cells, monocytes, macrophages, Langerhans cells, dendritic cells, subsets of activated T cells, and thymic epithelium. Under inflammatory conditions, CD74 expression may be observed in endothelial and certain epithelial cells. CD74 expression has been observed in ~90% of B-cell cancers evaluated, as well as the majority of cell lines derived from these cancers.CD74 is a marker for distinguishing atypical fibroxanthoma from malignant fibrous histiocytoma, and it is also a useful marker for distinguishing leiomyosarcoma from leiomyoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, Mouse
7 ml more info 14 days
€187,20 Add to cart
