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CD74 [LN-2]
Description Cluster of Differentiation 74 (CD74) is a type II transmembrane protein. In normal tissues, CD74 is expressed in B cells, monocytes, macrophages, Langerhans cells, dendritic cells, subsets of activated T cells, and thymic epithelium. Under inflammatory conditions, CD74 expression may be observed in endothelial and certain epithelial cells. CD74 expression has been observed in ~90% of B-cell cancers evaluated, as well as the majority of cell lines derived from these cancers.CD74 is a marker for distinguishing atypical fibroxanthoma from malignant fibrous histiocytoma, and it is also a useful marker for distinguishing leiomyosarcoma from leiomyoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, Mouse 
1 ml more info 
14 days 
€361,40 Add to cart -
CD74 [LN-2]
Description Cluster of Differentiation 74 (CD74) is a type II transmembrane protein. In normal tissues, CD74 is expressed in B cells, monocytes, macrophages, Langerhans cells, dendritic cells, subsets of activated T cells, and thymic epithelium. Under inflammatory conditions, CD74 expression may be observed in endothelial and certain epithelial cells. CD74 expression has been observed in ~90% of B-cell cancers evaluated, as well as the majority of cell lines derived from these cancers.CD74 is a marker for distinguishing atypical fibroxanthoma from malignant fibrous histiocytoma, and it is also a useful marker for distinguishing leiomyosarcoma from leiomyoma. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Baboon, Mouse
7 ml more info 14 days
€187,20 Add to cart -
Macrophage L1 Protein [MAC387]
Description Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupfferā€™s cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Baboon, Monkey, Bovine,Pig (Porcine), Goat, Horse, Cat, Dog (Canine), Rabbit, Guinea Pig, Rat, Mouse
1 ml more info 14 days
€361,40 Add to cart
