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CD57/B3GAT1 [NK-1]
Description CD57 is expressed on a natural killer (NK) cell subset, T cell subset, brain, neuroectodermal tumors, small cell lung carcinoma, prostate carcinomas, nerve sheath tissue s and their tumor counterparts. In a panel of antibody, the anti -CD57 antibody may be useful for the identification of T-cell large granular lymphocyte disorders, oligodendrogliomas, and neuroendocrine tumors. CD57 may a ssist in the identification of lymph ocytic and histiocytic (L&H) cells of lymphocyte predominant Hodgkin’s disease. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human 
1 ml more info 
14 days 
€361,40 Add to cart -
CD57/B3GAT1 [NK-1]
Description CD57 is expressed on a natural killer (NK) cell subset, T cell subset, brain, neuroectodermal tumors, small cell lung carcinoma, prostate carcinomas, nerve sheath tissue s and their tumor counterparts. In a panel of antibody, the anti -CD57 antibody may be useful for the identification of T-cell large granular lymphocyte disorders, oligodendrogliomas, and neuroendocrine tumors. CD57 may a ssist in the identification of lymph ocytic and histiocytic (L&H) cells of lymphocyte predominant Hodgkin’s disease. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
CD6 [3F7B5]
Description CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
CD6 [3F7B5]
Description CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
CD63 [NKI-C3]
Description CD63 is a 53 kDa lysosomal membrane glycoprotein that has been identified as a platelet activation molecule that belongs to the tetraspanin family, which is characterized by the presence of four hydrophobic domains. CD63 can mediate signal transduction events that play a role in the regulation of cellular adhesion, cell differentiation, migration, carcinogenesis and tumor progression. CD63 shows a broad tissue distribution and is predominantly localized in cytoplasmic lysosomes. It is mainly present on platelet lysosomes, granulocytes, basophils and a small percentage of resting T cells, while it is also strongly expressed in early melanoma, breast carcinoma, merkel cell carcinoma, astrocytoma and lung adenocarcinoma. Recent reports also indicate that CD63 is a good prognostic biomarker for human astrocytomas and earlier stages of lung carcinoma. Additionally, CD63 has been useful in differentiating renal oncocytomas (RO) from eosinophilic variants of chromophobe renal cell carcinomas Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse
1 ml more info 14 days
€361,40 Add to cart -
CD63 [NKI-C3]
Description CD63 is a 53 kDa lysosomal membrane glycoprotein that has been identified as a platelet activation molecule that belongs to the tetraspanin family, which is characterized by the presence of four hydrophobic domains. CD63 can mediate signal transduction events that play a role in the regulation of cellular adhesion, cell differentiation, migration, carcinogenesis and tumor progression. CD63 shows a broad tissue distribution and is predominantly localized in cytoplasmic lysosomes. It is mainly present on platelet lysosomes, granulocytes, basophils and a small percentage of resting T cells, while it is also strongly expressed in early melanoma, breast carcinoma, merkel cell carcinoma, astrocytoma and lung adenocarcinoma. Recent reports also indicate that CD63 is a good prognostic biomarker for human astrocytomas and earlier stages of lung carcinoma. Additionally, CD63 has been useful in differentiating renal oncocytomas (RO) from eosinophilic variants of chromophobe renal cell carcinomas Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse
7 ml more info 14 days
€187,20 Add to cart -
Golgi Complex (Marker for Human Cells) [371-4]
Description This antibody recognizes an antigen associated with the Golgi complex in human cells only. It can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
TCL1 [TCL1/2079]
Description T-cell leukemia/lymphoma protein 1A (TCL1) is a member of the TCL1 family and enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. TCL1 promotes the nuclear translocation of AKT1 and enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. The expression of TCL1 is restricted to lymphoid cells. It is expressed early in lymphocyte differentiation. Strong expression of TCL1 is found in a subset of mantle zone B lymphocytes and is expressed to a lesser extent by follicle center cells. In B cell neoplasia, TCL1 immunoreactivity is found in the majority of B cell lymphomas including lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, Burkitt lymphoma, diffuse large B-cell lymphoma (60%), and primary cutaneous B cell lymphoma (55%). The expression of the TCL1 gene characterizes low-grade B cell lymphomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€374,40 Add to cart -
TCL1 [TCL1/2079]
Description T-cell leukemia/lymphoma protein 1A (TCL1) is a member of the TCL1 family and enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. TCL1 promotes the nuclear translocation of AKT1 and enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. The expression of TCL1 is restricted to lymphoid cells. It is expressed early in lymphocyte differentiation. Strong expression of TCL1 is found in a subset of mantle zone B lymphocytes and is expressed to a lesser extent by follicle center cells. In B cell neoplasia, TCL1 immunoreactivity is found in the majority of B cell lymphomas including lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, Burkitt lymphoma, diffuse large B-cell lymphoma (60%), and primary cutaneous B cell lymphoma (55%). The expression of the TCL1 gene characterizes low-grade B cell lymphomas. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
TDP43/TAR DNA binding protein-43 [3H8]
Description TDP43 or TAR DNA-binding protein 43 belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. It is also is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in TDP43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€546,00 Add to cart
