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  • Article number: MC0892
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    Nucleolin [364-5]

    Description Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. (Shipping Cost: €200.00)
    Host Mouse
    Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
    Reactivity Human
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €361,40 
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  • Article number: MC0892RTU7
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    Nucleolin [364-5]

    Description Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. (Shipping Cost: €200.00)
    Host Mouse
    Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
    Reactivity Human
    Unit 7 ml
    more info
    Normal leadtime 14 days
    Calculated total €187,20 
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  • Article number: RC0167
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    NUT/NUTM1 Polyclonal

    Description NUT is known to fuse with BRD3 and BRD4 in NUT midline carcinoma (NMC), a rare and aggressive human cancer. In the majority of NMCs (~75%), most of the coding sequence is fused with BRD4 creating chimeric genes that encode BRD-NUT fusion proteins. In other cases, it fuses with BRD3 or an unknown partner gene. This tumor is often termed NUT-variant. To date, NMCs are still frequently undiagnosed or misdiagnosed and there are no effective treatment options. (Shipping Cost: €200.00)
    Host Rabbit
    Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC)
    Reactivity Human
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €598,00 
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  • Article number: RM0147
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    OCT2 [EPR542]

    Description Octamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It specifically binds to the octamer motif (5-ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 is expressed in mature B cells, predominantly germinal center B cells. Low expression of OCT-2 has been found in immature B cells, T cells and myelomonocytic cells. OCT-2 reactivity in epithelial cells and neuronal cells has also been reported. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas. In a study on Hodgkin's lymphoma (HL), OCT-2 positivity has been observed in 15 out of 15 lymphocyte predominance HLs, but none of the 29 classic HLs. (Shipping Cost: €200.00)
    Host Rabbit
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €494,00 
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  • Article number: RM0147RTU7
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    OCT2 [EPR542]

    Description Octamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It specifically binds to the octamer motif (5-ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 is expressed in mature B cells, predominantly germinal center B cells. Low expression of OCT-2 has been found in immature B cells, T cells and myelomonocytic cells. OCT-2 reactivity in epithelial cells and neuronal cells has also been reported. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas. In a study on Hodgkin's lymphoma (HL), OCT-2 positivity has been observed in 15 out of 15 lymphocyte predominance HLs, but none of the 29 classic HLs. (Shipping Cost: €200.00)
    Host Rabbit
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 7 ml
    more info
    Normal leadtime 14 days
    Calculated total €254,80 
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  • Article number: MC0297
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    OCT2 [Oct2/2136]

    Description Octamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It specifically binds to the octamer motif (5-ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 is expressed in mature B cells, predominantly germinal center B cells. Low expression of OCT-2 has been found in immature B cells, T cells and myelomonocytic cells. OCT-2 reactivity in epithelial cells and neuronal cells has also been reported. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas. In a study on Hodgkin's lymphoma (HL), OCT-2 positivity has been observed in 15 out of 15 lymphocyte predominance HLs, but none of the 29 classic HLs. (Shipping Cost: €200.00)
    Host Mouse
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €374,40 
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  • Article number: MC0297RTU7
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    OCT2 [Oct2/2136]

    Description Octamer transcription factor-2 (OCT-2) possesses a leucine zipper domain and belongs to the POU family of transcription factors. It specifically binds to the octamer motif (5-ATTTCAT-3), activates immunoglobulin gene expression and regulates transcription in a number of tissues. OCT-2 is important for the expression of B cell specific genes, such as CD20 and CRISP-3. OCT-2 is expressed in mature B cells, predominantly germinal center B cells. Low expression of OCT-2 has been found in immature B cells, T cells and myelomonocytic cells. OCT-2 reactivity in epithelial cells and neuronal cells has also been reported. The OCT-2 antibody labels various B cell lymphomas with strong expression in germinal center-derived lymphomas. In a study on Hodgkin's lymphoma (HL), OCT-2 positivity has been observed in 15 out of 15 lymphocyte predominance HLs, but none of the 29 classic HLs. (Shipping Cost: €200.00)
    Host Mouse
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 7 ml
    more info
    Normal leadtime 14 days
    Calculated total €187,20 
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  • Article number: MC0561
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    OCT3/4 [C-10]

    Description Transcription factors containing the POU homeo domain have been shown to be important regulators of tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA. The versatility of POU protein operation is additionally conferred at the dimerization level. Oct-3 (also known as Oct-4) is a mammalian POU transcription factor expressed by early embryo cells and germ cells. Oct-3/4 is essential for the identity of the pluripotential founder cell population in the mammalian embryo. A critical amount of Oct-3/4 is required to sustain stem-cell self renewal, and up or down regulation induce divergent developmental programmes. Two isoforms of Oct-3, termed Oct-3A and Oct-3B, are generated by alternative splicing. The gene which encodes Oct-3/4 maps to human chromosome 6p21.3 . Oct-3/4 (C-10) is r
    Host Mouse
    Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
    Reactivity Human, Mouse, Rat
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €361,40 
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  • Article number: MC0561RTU7
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    OCT3/4 [C-10]

    Description Transcription factors containing the POU homeo domain have been shown to be important regulators of tissue-specific gene expression in lymphoid and pituitary differentiation and in early mammalian development. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA. The versatility of POU protein operation is additionally conferred at the dimerization level. Oct-3 (also known as Oct-4) is a mammalian POU transcription factor expressed by early embryo cells and germ cells. Oct-3/4 is essential for the identity of the pluripotential founder cell population in the mammalian embryo. A critical amount of Oct-3/4 is required to sustain stem-cell self renewal, and up or down regulation induce divergent developmental programmes. Two isoforms of Oct-3, termed Oct-3A and Oct-3B, are generated by alternative splicing. The gene which encodes Oct-3/4 maps to human chromosome 6p21.3 . Oct-3/4 (C-10) is r
    Host Mouse
    Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
    Reactivity Human, Mouse, Rat
    Unit 7 ml
    more info
    Normal leadtime 14 days
    Calculated total €187,20 
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  • Article number: RM0148
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    OCT4 [MD192R]

    Description OCT-4, also known as OTF3 or POU5F1, is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. It can specifically bind to the octamer motif (5'-ATTTCAT-3'), and it is critical for the self-renewal of embryonic stem cells. Overall, OCT-4 is a key regulator of selfrenewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect some aspects of tumor behavior such as tumor recurrence or resistance to therapies. OCT- 4 is expressed in undifferentiated pluriopotency cells, germ cells in ovary and testes. OCT-4 is a sensitive and specific marker for germ cell tumors. It is consistently detected in carcinoma in situ/gonadoblastoma, seminomas, germinoma, dysgerminoma, and embryonal carcinoma but not in the differentiated components of nonseminomas, i.e., teratomas, yolk sac tumors, and choriocarcinomas. An antibody to OCT-4 is useful
    Host Rabbit
    Application Immunohistochemistry (IHC)
    Reactivity Human
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €416,00 
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