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BLC/BCA-1/CXCL13/B lymphocyte chemoattractant Polyclonal
Description Burkitt’s lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B cell migration into splenic and Peyer’s patch follicles. BLC expression in Peyer’s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation. (Shipping Cost: €200.00) Host Rabbit Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Dog 
1 ml more info 
14 days 
€494,00 Add to cart -
BLC/BCA-1/CXCL13/B lymphocyte chemoattractant Polyclonal
Description Burkitt’s lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B cell migration into splenic and Peyer’s patch follicles. BLC expression in Peyer’s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation. (Shipping Cost: €200.00) Host Rabbit Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Dog
7 ml more info 14 days
€254,80 Add to cart -
CD64/IGFR1 Polyclonal
Description This antibody recognizes CD64 also known as FcRI. CD64 is a high affinity activatory receptor for IgG2a and a low affinity receptor for IgG2b and IgG3 type antibodies. The interaction between Fc receptors and antibodies play important roles in both the innate and adaptive immune responses. CD64 through binding of the Fc segment of IgG, mediates phagocytosis and plays a role in antibody-dependent cellular cytotoxicity and clearance of immune complexes. In addition, CD64 also functions as an antigen capture for presentation to T-cells and also mediates the release of cytokines and reactive oxygen intermediates including interleukin (IL)-1, IL-6 and tumor necrosis factor (TNF) alpha. It is constitutively expressed on monocytes and macrophages, germinal centre dendritic cells and early myeloid lineage cells, but not lymphocytes. Expression on monocytes can be strongly upregulated by treatment with interferon (IFN) gamma or G-CSF, and can be induced on neutrophils and eosinophils by IFN gam Host Rabbit Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€455,00 Add to cart -
CD64/IGFR1 Polyclonal
Description This antibody recognizes CD64 also known as FcRI. CD64 is a high affinity activatory receptor for IgG2a and a low affinity receptor for IgG2b and IgG3 type antibodies. The interaction between Fc receptors and antibodies play important roles in both the innate and adaptive immune responses. CD64 through binding of the Fc segment of IgG, mediates phagocytosis and plays a role in antibody-dependent cellular cytotoxicity and clearance of immune complexes. In addition, CD64 also functions as an antigen capture for presentation to T-cells and also mediates the release of cytokines and reactive oxygen intermediates including interleukin (IL)-1, IL-6 and tumor necrosis factor (TNF) alpha. It is constitutively expressed on monocytes and macrophages, germinal centre dendritic cells and early myeloid lineage cells, but not lymphocytes. Expression on monocytes can be strongly upregulated by treatment with interferon (IFN) gamma or G-CSF, and can be induced on neutrophils and eosinophils by IFN gam Host Rabbit Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
7 ml more info 14 days
€254,80 Add to cart -
Cereblon/CRBN Polyclonal
Description Cereblon or CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. Cereblon functions energy metabolism, learning and memory. Cereblon acts as a protease in mitochondria and regulates the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding Cereblon belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the Cereblon gene are associated with mild mental retardation. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€494,00 Add to cart -
Chromogranin B Polyclonal
Description Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA, Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€374,40 Add to cart -
Chromogranin B Polyclonal
Description Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver. (Shipping Cost: €200.00) Host Rabbit Application Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA, Western Blot (WB) Reactivity Human, Mouse, Rat
7 ml more info 14 days
€163,80 Add to cart -
Complement C4 Polyclonal
Description This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
EB3 Polyclonal
Description Belongs to the MAPRE family. Predominantly expressed in brain and muscle. May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€494,00 Add to cart -
EB3 Polyclonal
Description Belongs to the MAPRE family. Predominantly expressed in brain and muscle. May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. (Shipping Cost: €200.00) Host Rabbit Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€201,50 Add to cart
