You are here
-
PLA2R/Phospholipase A2 receptor 1 [12-6-5]
Description This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified. Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of l Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human 
1 ml more info 
14 days 
€401,70 Add to cart -
PLA2R/Phospholipase A2 receptor 1 [12-6-5]
Description This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified. Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of l Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
Pneumocystis carinii/P. jiroveci [3F6]
Description Pneumocystis is a genus of fungi which can be pathogenic in mammals. Pneumocystis carinii, also referred to as Pneumocystis jiroveci, is a microscopic fungus that exists in the lungs of many humans. This fungus is normally benign, but it can cause Pneumocystis carinii pneumonia (PCP) in immunocompromised individuals. During PCP, Pneumocystis carinii deteriorates the basement membrane of the lung, causing a rise in LDH levels and compromising gas exchange. Oxygen is less able to diffuse into the blood, leading to hypoxia, which, along with high arterial CO2 levels, stimulates ventilation, thereby causing dyspnea. The fungus can also invade other visceral organs, such as the liver, spleen and kidney. Symptoms of Pneumocystis carinii infection include shortness of breath, non-productive cough, low grade fever, weight loss and night sweats. This disease can be fatal if not treated aggressively. This antibody reacts with a 82 kDa polypeptide specific to P. carinii. It does not cross-react Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Pneumocystis jiroveci infected tissues
1 ml more info 14 days
€361,40 Add to cart -
Pneumocystis carinii/P. jiroveci [3F6]
Description Pneumocystis is a genus of fungi which can be pathogenic in mammals. Pneumocystis carinii, also referred to as Pneumocystis jiroveci, is a microscopic fungus that exists in the lungs of many humans. This fungus is normally benign, but it can cause Pneumocystis carinii pneumonia (PCP) in immunocompromised individuals. During PCP, Pneumocystis carinii deteriorates the basement membrane of the lung, causing a rise in LDH levels and compromising gas exchange. Oxygen is less able to diffuse into the blood, leading to hypoxia, which, along with high arterial CO2 levels, stimulates ventilation, thereby causing dyspnea. The fungus can also invade other visceral organs, such as the liver, spleen and kidney. Symptoms of Pneumocystis carinii infection include shortness of breath, non-productive cough, low grade fever, weight loss and night sweats. This disease can be fatal if not treated aggressively. This antibody reacts with a 82 kDa polypeptide specific to P. carinii. It does not cross-react Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Pneumocystis jiroveci infected tissues
7 ml more info 14 days
€187,20 Add to cart -
Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) [3D3]
Description Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunofluorescence (IF), Western Blot (WB) Reactivity Human, Rabbit, Rat
1 ml more info 14 days
€361,40 Add to cart -
Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) [3D3]
Description Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunofluorescence (IF), Western Blot (WB) Reactivity Human, Rabbit, Rat
7 ml more info 14 days
€187,20 Add to cart -
Prolactin Receptor [B6.2]
Description Prolactin is a peptide hormone secreted by the anterior pituitary that is necessary for the proliferation and differentiation of the mammary glands. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth, differentiating and anti-apoptotic factor. Prolactin is secreted by lactotrophs in the anterior pituitary. Prolactin producing cells make up approximately 20 percent of the pituitary. Elevated counts of these cells have been observed in pregnant women, newborns and in multiparous women. An antibody to prolactin is useful for the identification of pituitary tumors (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Prolactin Receptor [B6.2]
Description Prolactin is a peptide hormone secreted by the anterior pituitary that is necessary for the proliferation and differentiation of the mammary glands. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth, differentiating and anti-apoptotic factor. Prolactin is secreted by lactotrophs in the anterior pituitary. Prolactin producing cells make up approximately 20 percent of the pituitary. Elevated counts of these cells have been observed in pregnant women, newborns and in multiparous women. An antibody to prolactin is useful for the identification of pituitary tumors (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Prostein [A5]
Description PSA, prostate specific antigen, is the classic indicator for transformed pro-state tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia. Prostein, also designated Prostate cancer-associated protein 6, is a prostate-specific, 553 amino acid transmembrane protein that is upregulated by androgens. It is considered a marker for prostate cells since it is expressed in all prostatic glandular cells as well as in normal and cancerous prostate tissues. Since it is able to elicit a tumor-directed cytotoxic T cell response, Prostein may be used as a target for the development of PSA- and T cell-based therapeutic strategies for prostate cancer. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€361,40 Add to cart -
pS2 Estrogen Inducible Protein [GE2]
Description This antibody specifically recognizes 6.5 kD human pS2 Estrogen-Regulated Protein. pS2 is specifically expressed and secreted by ER-mucosa cells of the normal stomach (antrum and body) of both female and male individuals. Primary breast tumors have been shown to express pS2 in ER+ primary breast tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Cynomolgus Monkey
1 ml more info 14 days
€361,40 Add to cart
