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Glucokinase/GCK Polyclonal
Description Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage (Shipping Cost: €200.00) Host Rabbit Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat 
1 ml more info 
14 days 
€494,00 Add to cart -
Growth Hormone (HGH) [GH/1450]
Description Growth hormone (GH or hGH), also known as somatotropin or somatropin, is a peptide hormone that is produced and secreted by somatotrophs of the anterior pituitary gland. GH exerts a wide variety of biological actions in many different tissues and cell types. The actions of GH at the cellular level can be divided into three categories: those affecting mitogenesis, differentiation, and metabolism. The GH antibody specifically labels somatotrophs in pituitary in normal tissues. It is useful in classification of pituitary tumor. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 14 days
€361,40 Add to cart -
Growth Hormone (HGH) [GH/1450]
Description Growth hormone (GH or hGH), also known as somatotropin or somatropin, is a peptide hormone that is produced and secreted by somatotrophs of the anterior pituitary gland. GH exerts a wide variety of biological actions in many different tissues and cell types. The actions of GH at the cellular level can be divided into three categories: those affecting mitogenesis, differentiation, and metabolism. The GH antibody specifically labels somatotrophs in pituitary in normal tissues. It is useful in classification of pituitary tumor. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Hamartin/TSC1 [C-8]
Description Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each ther forming a cystoplasmic complex. Hamartin interacts with the ezrinradixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Hamartin/TSC1 [C-8]
Description Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each ther forming a cystoplasmic complex. Hamartin interacts with the ezrinradixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney. (Shipping Cost: €200.00) Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
HCV Core NS4 [5D4/10E7]
Description The Hep C (Hepatitis C) is a small, enveloped, single-stranded, positive sense RNA virus belonging to the family Flaviviridae. Transmission of the virus occurs when blood from an infected individual enters the body of an uninfected individual. Hep C primarily replicates within hepatocytes in the liver, and circulating Hep C particles bind to receptors on the surface and enter these cells. Hep C replicates quickly, producing approximately one trillion particles each day in infected individuals. Hep C RNA polymerase has no proofreading function, so the virus has an exceptionally high mutation rate which may help it elude the host's immune system. Hep C infection results in chronic infections, liver cirrhosis, and hepatocellular carcinoma in most people. Hep C NS3 (nonstructural protein 3) has both protease and helicase activities and is essential for Hep C replication and proliferation. Hep C NS4 (nonstructural protein 4) augments the proteolytic activity of Hep C NS3 through protein-pro Host Mouse Application Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
HCV Core NS4 [5D4/10E7]
Description The Hep C (Hepatitis C) is a small, enveloped, single-stranded, positive sense RNA virus belonging to the family Flaviviridae. Transmission of the virus occurs when blood from an infected individual enters the body of an uninfected individual. Hep C primarily replicates within hepatocytes in the liver, and circulating Hep C particles bind to receptors on the surface and enter these cells. Hep C replicates quickly, producing approximately one trillion particles each day in infected individuals. Hep C RNA polymerase has no proofreading function, so the virus has an exceptionally high mutation rate which may help it elude the host's immune system. Hep C infection results in chronic infections, liver cirrhosis, and hepatocellular carcinoma in most people. Hep C NS3 (nonstructural protein 3) has both protease and helicase activities and is essential for Hep C replication and proliferation. Hep C NS4 (nonstructural protein 4) augments the proteolytic activity of Hep C NS3 through protein-pro Host Mouse Application Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
HDAC1/HD1 [10E2]
Description Acetylation of the histone tail causes chromatin to adopt an “open” conformation, allowing increased accessibility of transcription factors to DNA. The identification of histone acetyltransferases (HATs) and their large multiprotein complexes has yielded important insights into how these enzymes regulate transcription. HAT complexes interact with sequence-specific activator proteins to target specific genes. In addition to histones, HATs can acetylate non-histone proteins, suggesting multiple roles for these enzymes. In contrast, histone deacetylation promotes a “closed” chromatin conformation and typically leads to repression of gene activity. Mammalian histone deacetylases can be divided into three classes on the basis of their similarity to various yeast deacetylases. Class I (HDACs 1, 2, 3 and 8) proteins are related to the yeast Rpd3-like proteins, those in class II (HDACs 4, 5, 6, 7, 9 and 10) are related to yeast Hda1-like proteins and class III proteins are related to the yeast Host Mouse Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€361,40 Add to cart -
Heat Shock Protein (HSP27) [G3.1]
Description HSP 27 also known as 24K estrogen-regulated protein or HSP 28 is a small heat shock protein that has been shown to correlate with the expression of estrogen-receptor. Immunohistochemical studies of HSP 27 has shown that it is localized mainly in the female reproductive tract and in ER and PR positive breast tumor cell lines. Increased levels of HSP 27 have been shown to correlate with the presence of ER and PR in human breast tumor biopsy samples. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Chimpanzee, Monkey, Sheep, Rat, Mouse, Chicken
1 ml more info 14 days
€361,40 Add to cart -
Heat Shock Protein (HSP27) [G3.1]
Description HSP 27 also known as 24K estrogen-regulated protein or HSP 28 is a small heat shock protein that has been shown to correlate with the expression of estrogen-receptor. Immunohistochemical studies of HSP 27 has shown that it is localized mainly in the female reproductive tract and in ER and PR positive breast tumor cell lines. Increased levels of HSP 27 have been shown to correlate with the presence of ER and PR in human breast tumor biopsy samples. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Chimpanzee, Monkey, Sheep, Rat, Mouse, Chicken
7 ml more info 14 days
€187,20 Add to cart
