You are here
-
PLA2R/Phospholipase A2 receptor 1 [12-6-5]
Description This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified. Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of l Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human 
7 ml more info 
14 days 
€254,80 Add to cart -
Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) [3D3]
Description Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunofluorescence (IF), Western Blot (WB) Reactivity Human, Rabbit, Rat
1 ml more info 14 days
€361,40 Add to cart -
Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) [3D3]
Description Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunofluorescence (IF), Western Blot (WB) Reactivity Human, Rabbit, Rat
7 ml more info 14 days
€187,20 Add to cart -
PR [SP2]
Description The human progesterone receptor (PR), is a ligand-activated transcription factor and is a member of the steroid receptor family. PR exists in humans as two isoforms. PR is predominantly expressed in female sex steroid responsive tissues such as the mammary gland, uterus and ovary, but is also found in other tissues such as prostate stromal cells, anterior pituitary gland, and endocrine cells of the Langerhans' islets. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry on paraffin sections (IHC-P), Western Blot (WB) Reactivity Human, Rat
1 ml more info 14 days
€546,00 Add to cart -
PR [SP2]
Description The human progesterone receptor (PR), is a ligand-activated transcription factor and is a member of the steroid receptor family. PR exists in humans as two isoforms. PR is predominantly expressed in female sex steroid responsive tissues such as the mammary gland, uterus and ovary, but is also found in other tissues such as prostate stromal cells, anterior pituitary gland, and endocrine cells of the Langerhans' islets. (Shipping Cost: €200.00) Host Rabbit Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry on paraffin sections (IHC-P), Western Blot (WB) Reactivity Human, Rat
7 ml more info 14 days
€348,40 Add to cart -
Prolactin Receptor [B6.2]
Description Prolactin is a peptide hormone secreted by the anterior pituitary that is necessary for the proliferation and differentiation of the mammary glands. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth, differentiating and anti-apoptotic factor. Prolactin is secreted by lactotrophs in the anterior pituitary. Prolactin producing cells make up approximately 20 percent of the pituitary. Elevated counts of these cells have been observed in pregnant women, newborns and in multiparous women. An antibody to prolactin is useful for the identification of pituitary tumors (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Prolactin Receptor [B6.2]
Description Prolactin is a peptide hormone secreted by the anterior pituitary that is necessary for the proliferation and differentiation of the mammary glands. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. Prolactin has important cell cycle related functions as a growth, differentiating and anti-apoptotic factor. Prolactin is secreted by lactotrophs in the anterior pituitary. Prolactin producing cells make up approximately 20 percent of the pituitary. Elevated counts of these cells have been observed in pregnant women, newborns and in multiparous women. An antibody to prolactin is useful for the identification of pituitary tumors (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
pS2 Estrogen Inducible Protein [GE2]
Description This antibody specifically recognizes 6.5 kD human pS2 Estrogen-Regulated Protein. pS2 is specifically expressed and secreted by ER-mucosa cells of the normal stomach (antrum and body) of both female and male individuals. Primary breast tumors have been shown to express pS2 in ER+ primary breast tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Cynomolgus Monkey
1 ml more info 14 days
€361,40 Add to cart -
pS2 Estrogen Inducible Protein [GE2]
Description This antibody specifically recognizes 6.5 kD human pS2 Estrogen-Regulated Protein. pS2 is specifically expressed and secreted by ER-mucosa cells of the normal stomach (antrum and body) of both female and male individuals. Primary breast tumors have been shown to express pS2 in ER+ primary breast tumors. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Cynomolgus Monkey
7 ml more info 14 days
€187,20 Add to cart -
PSA (Prostate Specific Antigen) [A67-B/E3]
Description Prostate-specific antigen (PSA) is a serine protease member of the human glandular kallikrein family. It is synthesized in the prostate ductal and acinar epithelium and diffused into serum. It is found in normal, hyperplastic, and malignant prostate tissue. Low expression of PSA has been reported in other normal or tumor tissues such as urethral, periurethral, and perianal glands, salivary duct carcinoma, and rare mammary carcinomas. Although low PSA expression has been found in other tissues, PSA is still a specific and sensitive marker for immunohistochemical analysis of tumors with prostate epithelial cell differentiation. It is valuable in the identification of metastatic tumors of prostatic origin. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart
