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Histone H3 antibody
Description Purified Polyclonal Histone H3 antibody (Shipping Cost: €205.00) Host Rabbit Application Western Blot (WB),Immunofluorescence (IF),Immunocytochemistry (ICC) Reactivity Mouse,Rat,Bovine,Chicken,Pig (Porcine),Rabbit Specificity Recognizes endogenous levels of Histone H3 protein -
Actin alpha Sarcomeric [5C5]
Description Actin is a cytoskeletal protein that regulates cell motility, secretion, phagocytosis and cytokinesis. The NH2-terminal of actin may function as antigen. This terminal may also modulate actin interactions and may associate with proteins such as myosin. This antibody is specific for α-skeletal and α-cardiac muscle actins as characterized by ELISA, immunoblot and immunohistochemistry. The antibody shows wide species cross reactivity with tissue from human, sheep, bovine, rabbit, guinea pig, rat, frog, snake, and carp. However, it does not react with smooth muscle tissue. (Shipping Cost: €200.00) Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Sheep, Bovine, Rabbit, Guinea Pig, Rat, Frog, Snake, Carp -
Actin alpha Sarcomeric [5C5]
Description Actin is a cytoskeletal protein that regulates cell motility, secretion, phagocytosis and cytokinesis. The NH2-terminal of actin may function as antigen. This terminal may also modulate actin interactions and may associate with proteins such as myosin. This antibody is specific for α-skeletal and α-cardiac muscle actins as characterized by ELISA, immunoblot and immunohistochemistry. The antibody shows wide species cross reactivity with tissue from human, sheep, bovine, rabbit, guinea pig, rat, frog, snake, and carp. However, it does not react with smooth muscle tissue. (Shipping Cost: €200.00) Host Mouse Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Sheep, Bovine, Rabbit, Guinea Pig, Rat, Frog, Snake, Carp -
CD5 [C5/473&CD5/54/F6]
Description CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation. CD5 antibody labels a variety of T lymphocytes, mantle zone lymphocytes and a small subset of B lymphocytes. In tumors, CD5 is expressed on T-cell malignancies, Bcell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), and mantle-cell lymphoma. It is a useful diagnostic tool for these tumors. In addition, anti-CD5 is helpful in diagnosis of thymic carcinoma (CD5 positive). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rabbit, Rat, Bovine -
CD5 [C5/473&CD5/54/F6]
Description CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation. CD5 antibody labels a variety of T lymphocytes, mantle zone lymphocytes and a small subset of B lymphocytes. In tumors, CD5 is expressed on T-cell malignancies, Bcell chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), and mantle-cell lymphoma. It is a useful diagnostic tool for these tumors. In addition, anti-CD5 is helpful in diagnosis of thymic carcinoma (CD5 positive). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rabbit, Rat, Bovine -
CD68 [KP1]
Description CD68 is expressed on macrophages and monocytes. KP -1 is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. KP-1 reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Tumors of lymphoid origin are usually not stained. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rabbit, Monkey, Cat -
CD68 [KP1]
Description CD68 is expressed on macrophages and monocytes. KP -1 is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. KP-1 reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Tumors of lymphoid origin are usually not stained. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rabbit, Monkey, Cat -
Cytokeratin Basic [AE3]
Description Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50’, 48, 46, 45, and 40kDa. The basic keratin s have molecular weights of 65-67, 64, 59, 58, 56 and 52kDa. Members of acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with cell type, differentiation status and environment. Many studies have shown the us efulness of keratins as markers in cancer research and tumor diagnosis. AE1 labels most acidic keratins; therefore, it is a broadly reactive antibody staining most epithelia and their neoplasms. AE1 is particularly suited to distinguish poorly differentiat ed carcinomas from non-epithelial neoplasms. This marker stains both normal and neoplastic cells of epithelial origin. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Bovine, Dog (Canine), Rabbit, Mouse, Rat, Chicken -
Cytokeratin Basic [AE3]
Description Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50’, 48, 46, 45, and 40kDa. The basic keratin s have molecular weights of 65-67, 64, 59, 58, 56 and 52kDa. Members of acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with cell type, differentiation status and environment. Many studies have shown the us efulness of keratins as markers in cancer research and tumor diagnosis. AE1 labels most acidic keratins; therefore, it is a broadly reactive antibody staining most epithelia and their neoplasms. AE1 is particularly suited to distinguish poorly differentiat ed carcinomas from non-epithelial neoplasms. This marker stains both normal and neoplastic cells of epithelial origin. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Bovine, Dog (Canine), Rabbit, Mouse, Rat, Chicken -
GFAP [GA-5]
Description Glial fibrillary acidic protein (GFAP) is the subunit of the glial specific “intermediate” filament that include desmin filaments in smooth muscle, vimentin filaments in cultured fibroblasts, keratin filaments in epithelium and neurofilaments in neural cells. GFAP is a major product of astrocytic differentiation. Compared with special stains currently used to identify an astroglial component in brain tumors, GFAP staining is more sensitive. Further, the immunohistochemical staining method is useful in demonstrating reactive astrocytes, whether secondary to a brain tumor or to any other neuro-pathological condition. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Western Blot (WB) Reactivity Human, Mouse, Rat, Rabbit, Chicken, Bovine,Pig (Porcine)