CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

You are here

Search / "Guinea Pig" / "2-25LE"
  • Article number: MC0008
    Add to compare

    Blood Group Lewis B [2-25LE same as LWB01]

    Description The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Lewis blood group antigens are carbohydrate moieties structurally integrated in mucous secretions. Lewis antigen system alterations have been described in gastric carcinoma and associated lesions. Anomalous expression of Lewis B antigen has been found in some non-secretory gastric carcinomas and colorectal cancers. (Shipping Cost: €200.00)
    Host Mouse
    Application Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC)
    Reactivity Human, Guinea Pig
    Unit 1 ml
    more info
    Normal leadtime 14 days
    Calculated total €361,40 
    Add to cart