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CD63 [NKI-C3]
Description CD63 is a 53 kDa lysosomal membrane glycoprotein that has been identified as a platelet activation molecule that belongs to the tetraspanin family, which is characterized by the presence of four hydrophobic domains. CD63 can mediate signal transduction events that play a role in the regulation of cellular adhesion, cell differentiation, migration, carcinogenesis and tumor progression. CD63 shows a broad tissue distribution and is predominantly localized in cytoplasmic lysosomes. It is mainly present on platelet lysosomes, granulocytes, basophils and a small percentage of resting T cells, while it is also strongly expressed in early melanoma, breast carcinoma, merkel cell carcinoma, astrocytoma and lung adenocarcinoma. Recent reports also indicate that CD63 is a good prognostic biomarker for human astrocytomas and earlier stages of lung carcinoma. Additionally, CD63 has been useful in differentiating renal oncocytomas (RO) from eosinophilic variants of chromophobe renal cell carcinomas Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse 
1 ml more info 
14 days 
€361,40 Add to cart -
CD63 [NKI-C3]
Description CD63 is a 53 kDa lysosomal membrane glycoprotein that has been identified as a platelet activation molecule that belongs to the tetraspanin family, which is characterized by the presence of four hydrophobic domains. CD63 can mediate signal transduction events that play a role in the regulation of cellular adhesion, cell differentiation, migration, carcinogenesis and tumor progression. CD63 shows a broad tissue distribution and is predominantly localized in cytoplasmic lysosomes. It is mainly present on platelet lysosomes, granulocytes, basophils and a small percentage of resting T cells, while it is also strongly expressed in early melanoma, breast carcinoma, merkel cell carcinoma, astrocytoma and lung adenocarcinoma. Recent reports also indicate that CD63 is a good prognostic biomarker for human astrocytomas and earlier stages of lung carcinoma. Additionally, CD63 has been useful in differentiating renal oncocytomas (RO) from eosinophilic variants of chromophobe renal cell carcinomas Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse
7 ml more info 14 days
€187,20 Add to cart -
CD68 [KP1]
Description CD68 is expressed on macrophages and monocytes. KP -1 is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. KP-1 reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Tumors of lymphoid origin are usually not stained. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rabbit, Monkey, Cat
1 ml more info 14 days
€361,40 Add to cart -
Glypican-3 [1G12]
Description Glypican-3 (GPC3) is a member of the glypican family of glycosyl phosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans. GPC3 is a tissue and serum biomarker for the early detection of hepatocellular carcinoma. The anti-GPC3 antibody has been used to assess GPC3 expression in malignant and non-malignant liver tissue samples and for quantitative ELISA detection of GPC3 concentration in the serum. Capurro et al. have shown that GPC3 is expressed at the protein level by immunohistochemistry in most cases of primary liver cancer including small tumors, but is undetectable in normal liver and benign hepatic lesions. In addition, the authors found that GPC3 is significantly elevated in the serum of a large proportion of patients with Primary Liver Cancer. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Glypican-3 [1G12]
Description Glypican-3 (GPC3) is a member of the glypican family of glycosyl phosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans. GPC3 is a tissue and serum biomarker for the early detection of hepatocellular carcinoma. The anti-GPC3 antibody has been used to assess GPC3 expression in malignant and non-malignant liver tissue samples and for quantitative ELISA detection of GPC3 concentration in the serum. Capurro et al. have shown that GPC3 is expressed at the protein level by immunohistochemistry in most cases of primary liver cancer including small tumors, but is undetectable in normal liver and benign hepatic lesions. In addition, the authors found that GPC3 is significantly elevated in the serum of a large proportion of patients with Primary Liver Cancer. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Glypican-3 [GPC3/863]
Description Glypican-3 (GPC3) is a member of the glypican family of glycosyl phosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans. GPC3 is a tissue and serum biomarker for the early detection of hepatocellular carcinoma. The anti-GPC3 antibody has been used to assess GPC3 expression in malignant and non-malignant liver tissue samples and for quantitative ELISA detection of GPC3 concentration in the serum. Capurro et al. have shown that GPC3 is expressed at the protein level by immunohistochemistry in most cases of primary liver cancer including small tumors, but is undetectable in normal liver and benign hepatic lesions. In addition, the authors found that GPC3 is significantly elevated in the serum of a large proportion of patients with Primary Liver Cancer. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rat
1 ml more info 14 days
€361,40 Add to cart -
Glypican-3 [GPC3/863]
Description Glypican-3 (GPC3) is a member of the glypican family of glycosyl phosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans. GPC3 is a tissue and serum biomarker for the early detection of hepatocellular carcinoma. The anti-GPC3 antibody has been used to assess GPC3 expression in malignant and non-malignant liver tissue samples and for quantitative ELISA detection of GPC3 concentration in the serum. Capurro et al. have shown that GPC3 is expressed at the protein level by immunohistochemistry in most cases of primary liver cancer including small tumors, but is undetectable in normal liver and benign hepatic lesions. In addition, the authors found that GPC3 is significantly elevated in the serum of a large proportion of patients with Primary Liver Cancer. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Rat
7 ml more info 14 days
€187,20 Add to cart -
Golgi Complex (Marker for Human Cells) [371-4]
Description This antibody recognizes an antigen associated with the Golgi complex in human cells only. It can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
Granulocyte-Colony Stimulating Factor (G-CSF) (CSF3) [CSF3/900]
Description Belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Macaque
1 ml more info 14 days
€361,40 Add to cart -
Granulocyte-Colony Stimulating Factor (G-CSF) (CSF3) [CSF3/900]
Description Belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Macaque
7 ml more info 14 days
€187,20 Add to cart
