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Cytokeratin 19 [BA17]
Description Cytokeratin polypeptide 19 (CK19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. CK19 is synthesized mainly in embryonic and adult simple epithelia, but has also been found in non-keratinizing stratified epithelia as well. CK19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is different from other keratin-encoding genes. CK19 antibody is a useful tool for the identification of epithelial tumors. It is helpful in distinguishing hepatocellular carcinoma (CK19-) from cholangiocarcinoma (CK19+) or metastatic carcinoma in liver (CK19+). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse 
1 ml more info 
14 days 
€361,40 Add to cart -
Cytokeratin 19 [BA17]
Description Cytokeratin polypeptide 19 (CK19) is a type I intermediate filament protein that is expressed in stratified and simple-type epithelia. CK19 is synthesized mainly in embryonic and adult simple epithelia, but has also been found in non-keratinizing stratified epithelia as well. CK19 is the smallest known keratin and is remarkable in that, contrary to all other keratins, it does not have a designated partner for the formation of filaments, implying that regulation of its expression is different from other keratin-encoding genes. CK19 antibody is a useful tool for the identification of epithelial tumors. It is helpful in distinguishing hepatocellular carcinoma (CK19-) from cholangiocarcinoma (CK19+) or metastatic carcinoma in liver (CK19+). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin 20 [Ks20.8]
Description Intermediate-sized filament (IF) protein designated cytokeratin 20 (CK20) is a major cellular protein of mature enterocytes and goblet cells commonly found in mucosal epithelium of the mammalian gastrointestinal tract. Results strongly suggest that transcriptional regulation of keratin genes in the intestinal epithelium occurs at the level of both immature and terminally differentiated epithelial cells, and is tightly regulated during both fetal development and crypt-to-villus differentiation of the intestinal epithelium. CK20 has recently been reported to be useful to distinguish between primary and metastatic lung adenocarcinoma. CK20 expression was significantly more prevalent in adenocarcinoma that originated in the GI tract than that of pulmonary or breast origin. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€374,40 Add to cart -
Cytokeratin 20 [Ks20.8]
Description Intermediate-sized filament (IF) protein designated cytokeratin 20 (CK20) is a major cellular protein of mature enterocytes and goblet cells commonly found in mucosal epithelium of the mammalian gastrointestinal tract. Results strongly suggest that transcriptional regulation of keratin genes in the intestinal epithelium occurs at the level of both immature and terminally differentiated epithelial cells, and is tightly regulated during both fetal development and crypt-to-villus differentiation of the intestinal epithelium. CK20 has recently been reported to be useful to distinguish between primary and metastatic lung adenocarcinoma. CK20 expression was significantly more prevalent in adenocarcinoma that originated in the GI tract than that of pulmonary or breast origin. (Shipping Cost: €200.00) Host Mouse Application Immunohistochemistry (IHC), Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Western Blot (WB) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin 5/8 [C-50]
Description It reacts with keratin 5 (58kDa) and keratin 8 (52.5kDa). Simple epithelia express cytokeratin 8 in combination with 18. On the other hand, basal cells of stratified epithelia express cytokeratin 5 paired with 14. This antibody therefore, reacts with a wide range of epithelia and their carcinomas. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human,Pig (Porcine), Mouse, Rat, Hamster, Bovine, Dog (Canine), Sheep
1 ml more info 14 days
€361,40 Add to cart -
Cytokeratin 6 [LHK6]
Description The human type II Cytokeratin 6 (CK6; 56 kDa) is well known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or abnormal differentiation during wound healing, in several diseases (e.g. psoriasis, actinic keratosis) and in cancer. CK6 is expressed on stratified epithelia including oral mucosa, esophagus, basal layer of epidermis, the outer root sheath of hair follicles, and in glandular epithelia. CK6 is a marker of hyperproliferative and activated keratinocytes found in psoriasis. CK6 paired with CK5 is useful to differentiate mesothelioma (positive) from lung carcinoma (negative) or metastatic carcinoma (negative) in the pleura. CK5/6 has also been used to distinguish usual ductal hyperplasia of the breast (strong staining) from solid papillary DCIS (negative). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse
1 ml more info 14 days
€361,40 Add to cart -
Cytokeratin 6 [LHK6]
Description The human type II Cytokeratin 6 (CK6; 56 kDa) is well known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or abnormal differentiation during wound healing, in several diseases (e.g. psoriasis, actinic keratosis) and in cancer. CK6 is expressed on stratified epithelia including oral mucosa, esophagus, basal layer of epidermis, the outer root sheath of hair follicles, and in glandular epithelia. CK6 is a marker of hyperproliferative and activated keratinocytes found in psoriasis. CK6 paired with CK5 is useful to differentiate mesothelioma (positive) from lung carcinoma (negative) or metastatic carcinoma (negative) in the pleura. CK5/6 has also been used to distinguish usual ductal hyperplasia of the breast (strong staining) from solid papillary DCIS (negative). (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin Acid [AE1]
Description Each epithelium contains at least one acidic and one basic keratin. Anti-Cytokeratin clone AE1 labels most acidic keratins and stains most epithelia and their neoplasms. The antibody is suited to distinguish poorly differentiated carcinomas from non-epithelial neoplasms. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Bovine, Dog (Canine), Rabbit, Mouse, Rat, Chicken, Turtle
1 ml more info 14 days
€361,40 Add to cart -
Cytokeratin Acid [AE1]
Description Each epithelium contains at least one acidic and one basic keratin. Anti-Cytokeratin clone AE1 labels most acidic keratins and stains most epithelia and their neoplasms. The antibody is suited to distinguish poorly differentiated carcinomas from non-epithelial neoplasms. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Bovine, Dog (Canine), Rabbit, Mouse, Rat, Chicken, Turtle
7 ml more info 14 days
€187,20 Add to cart -
Cytokeratin Basic [AE3]
Description Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50’, 48, 46, 45, and 40kDa. The basic keratin s have molecular weights of 65-67, 64, 59, 58, 56 and 52kDa. Members of acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with cell type, differentiation status and environment. Many studies have shown the us efulness of keratins as markers in cancer research and tumor diagnosis. AE1 labels most acidic keratins; therefore, it is a broadly reactive antibody staining most epithelia and their neoplasms. AE1 is particularly suited to distinguish poorly differentiat ed carcinomas from non-epithelial neoplasms. This marker stains both normal and neoplastic cells of epithelial origin. (Shipping Cost: €200.00) Host Mouse Application Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Monkey, Bovine, Dog (Canine), Rabbit, Mouse, Rat, Chicken
1 ml more info 14 days
€361,40 Add to cart
