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GPC4 antibody
Description Mouse monoclonal GPC4 antibody (Shipping Cost: €205.00) Host Mouse Application ELISA,Immunofluorescence (IF),Western Blot (WB),Flow cytometry (FC) Reactivity Human,Mouse Concentration 1 mg/ml Specificity Human -
Blood Group Antigen Lewis A [7LE]
Description Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse -
Calcitonin Gene Related Peptide/CGRP [4901]
Description Calcitonin Gene Related Peptide or CGRP is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known. It is primarily produced in nervous tissue and its receptors are expressed throughout the body. CGRP is strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (PFA fixed), Immunohistochemistry on frozen sections (IHC-Fs), Immunoprecipitation (IP) Reactivity Human, Mouse, Rat, Dog Guinea Pig -
Cyclin D1 [DCS-6]
Description Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat -
Cyclin D1 [DCS-6]
Description Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat -
EMA/CA15.3/MUC1/Episialin/CD227 [139H2]
Description Mucins are a family of heavily glycosylated high molecular weight glycoproteins. Total 21 mucins have been identified to date. Mucins are well known for its involvement in the protection and lubrication of luminal epithelial surfaces. MUC1, a transmembrane mucins, has been shown to be involved in several signaling pathways, including Ras, beta-catenin, p120 catenin, p53 and estrogen receptor alpha. When MUC1 forms a complex with beta-catenin, it enters the nucleus to activate T-cell factor/leukocyte enhancing factor 1 transcription factors and gene expression. In addition, MUC1 may inhibit cell-cell and cell-stroma interactions and function as a signal transducer, participating in cancer progression. MUC1 is expressed in many types of epithelial cell in gastrointerstinal tract, lung, breast, pancreas and genitourinary tract. MUC1 is also detected in activated and unactivated T-cells. In some tumors derived from epithelial cells, MUC1 expression is associated with tumor type and invasiv Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse -
EMA/CA15.3/MUC1/Episialin/CD227 [139H2]
Description Mucins are a family of heavily glycosylated high molecular weight glycoproteins. Total 21 mucins have been identified to date. Mucins are well known for its involvement in the protection and lubrication of luminal epithelial surfaces. MUC1, a transmembrane mucins, has been shown to be involved in several signaling pathways, including Ras, beta-catenin, p120 catenin, p53 and estrogen receptor alpha. When MUC1 forms a complex with beta-catenin, it enters the nucleus to activate T-cell factor/leukocyte enhancing factor 1 transcription factors and gene expression. In addition, MUC1 may inhibit cell-cell and cell-stroma interactions and function as a signal transducer, participating in cancer progression. MUC1 is expressed in many types of epithelial cell in gastrointerstinal tract, lung, breast, pancreas and genitourinary tract. MUC1 is also detected in activated and unactivated T-cells. In some tumors derived from epithelial cells, MUC1 expression is associated with tumor type and invasiv Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse -
EMA/CA15.3/MUC1/Episialin/CD227 [SPM492]
Description Mucins are a family of heavily glycosylated high molecular weight glycoproteins. Total 21 mucins have been identified to date. Mucins are well known for its involvement in the protection and lubrication of luminal epithelial surfaces. MUC1, a transmembrane mucins, has been shown to be involved in several signaling pathways, including Ras, beta-catenin, p120 catenin, p53 and estrogen receptor alpha. When MUC1 forms a complex with beta-catenin, it enters the nucleus to activate T-cell factor/leukocyte enhancing factor 1 transcription factors and gene expression. In addition, MUC1 may inhibit cell-cell and cell-stroma interactions and function as a signal transducer, participating in cancer progression. MUC1 is expressed in many types of epithelial cell in gastrointerstinal tract, lung, breast, pancreas and genitourinary tract. MUC1 is also detected in activated and unactivated T-cells. In some tumors derived from epithelial cells, MUC1 expression is associated with tumor type and invasiv Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse -
EMA/CA15.3/MUC1/Episialin/CD227 [SPM492]
Description Mucins are a family of heavily glycosylated high molecular weight glycoproteins. Total 21 mucins have been identified to date. Mucins are well known for its involvement in the protection and lubrication of luminal epithelial surfaces. MUC1, a transmembrane mucins, has been shown to be involved in several signaling pathways, including Ras, beta-catenin, p120 catenin, p53 and estrogen receptor alpha. When MUC1 forms a complex with beta-catenin, it enters the nucleus to activate T-cell factor/leukocyte enhancing factor 1 transcription factors and gene expression. In addition, MUC1 may inhibit cell-cell and cell-stroma interactions and function as a signal transducer, participating in cancer progression. MUC1 is expressed in many types of epithelial cell in gastrointerstinal tract, lung, breast, pancreas and genitourinary tract. MUC1 is also detected in activated and unactivated T-cells. In some tumors derived from epithelial cells, MUC1 expression is associated with tumor type and invasiv Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human, Mouse -
Heat Shock Protein (HSP60) (Mitochondrial Marker) [LK1]
Description Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone LK1, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) Reactivity Human, Mouse, Rat, Hamster, Sheep, Rabbit, Bovine, Dog (Canine),Pig (Porcine), Monkey, Chicken, Xenopus laevis, Drosophila