You are here
-
GPC4 antibody
Description Mouse monoclonal GPC4 antibody (Shipping Cost: €205.00) Host Mouse Application ELISA,Immunofluorescence (IF),Western Blot (WB),Flow cytometry (FC) Reactivity Human,Mouse Concentration 1 mg/ml Specificity Human 
100 ul more info 
5-7 days 
€288,00 Add to cart -
KRT20 antibody
Description Mouse Monoclonal KRT20 antibody (Shipping Cost: €205.00) Host Mouse Application ELISA,Western Blot (WB),Immunocytochemistry (ICC),Immunofluorescence (IF),Flow cytometry (FC) Concentration 1 mg/ml
100 ul more info 5-7 days
€328,50 Add to cart -
14.3.3 epsilon antibody
Host Mouse Application ELISA,Western Blot (WB),Flow cytometry (FC),Immunocytochemistry (ICC),Immunofluorescence (IF) Concentration 1 mg/ml Specificity Human
100 ul more info 5-7 days
€288,90 Add to cart -
Blood Group Antigen Lewis A [7LE]
Description Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse
1 ml more info 14 days
€361,40 Add to cart -
C5b9/TCC/MAC [aE11]
Description The complement component proteins: C2, C3, C4 and C5 are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. Activation of the complement system leads to the formation of C5b-9 terminal complex, and while C5b-9 can promote cell lysis, the sublytic assembly of C5b-9 on plasma membranes causes an opposite result and induces cell cycle activation and survival. C5b-9 can rescue oligodendrocytes from FAS-mediated apoptosis by regulating caspase-8 processing via PI 3-K signaling. C5b-9 may play a pro-inflammatory role in the acute phase of multiple sclerosis, but may also be neuroprotective during the chronic phase of the disease. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC)-F Reactivity Human, Horse,Pig (Porcine), Monkey, Baboon
1 ml more info 14 days
€429,00 Add to cart -
Calcitonin Gene Related Peptide/CGRP [4901]
Description Calcitonin Gene Related Peptide or CGRP is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known. It is primarily produced in nervous tissue and its receptors are expressed throughout the body. CGRP is strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (PFA fixed), Immunohistochemistry on frozen sections (IHC-Fs), Immunoprecipitation (IP) Reactivity Human, Mouse, Rat, Dog Guinea Pig
1 ml more info 14 days
€374,40 Add to cart -
CD130/gp130/IL-6RB [AN-H2]
Description The activation of the IL-6 protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL-6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the IL-6 receptor (IL-6R) and directly activate this protein. IL-6 first binds to IL-6R which subsequently associates with a gp130 dimer. The active signaling complex consists of at minimum IL-6, IL-6R and a dimer of two gp130 proteins that are linked by a disulfide bond. The second subunit of the IL-6 complex, gp130, also functions as a component of several additional receptor complexes including leukemia inhibitory factor (LIF), oncostatin M (OSM), ciliary neurotrophic factor (CNTF) and IL-11. LIF binds to the LIF receptor with low affinity and to a complex of the LIF receptor and gp130 with high affinity while OSM appears to bind to gp130 with low affinity and to a complex of gp130 and the LIF receptor with high affinity. The protein encoded by this gene is a signal transducer shared by Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€374,40 Add to cart -
CD130/gp130/IL-6RB [AN-H2]
Description The activation of the IL-6 protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL-6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the IL-6 receptor (IL-6R) and directly activate this protein. IL-6 first binds to IL-6R which subsequently associates with a gp130 dimer. The active signaling complex consists of at minimum IL-6, IL-6R and a dimer of two gp130 proteins that are linked by a disulfide bond. The second subunit of the IL-6 complex, gp130, also functions as a component of several additional receptor complexes including leukemia inhibitory factor (LIF), oncostatin M (OSM), ciliary neurotrophic factor (CNTF) and IL-11. LIF binds to the LIF receptor with low affinity and to a complex of the LIF receptor and gp130 with high affinity while OSM appears to bind to gp130 with low affinity and to a complex of gp130 and the LIF receptor with high affinity. The protein encoded by this gene is a signal transducer shared by Host Mouse Application ELISA, Flow cytometry (FC), Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€187,20 Add to cart -
CD71 (Transferrin Receptor) [TFRC/1817]
Description CD71, the transferrin receptor, is a type II trans-membrane homodimer glycoprotein (180 kDa) involved in the cellular uptake of iron via internalization of iron-loaded transferring. CD71 is highly expressed in immature erythroid cells, placental tissue and rapidly dividing cells. Loss of CD71 is observed in mature erythrocytes. Over expression of CD71 has also been described for various types of cancers including lung, colon, breast and pancreas. CD71 antibody is useful in identifying erythroid precursors. (Shipping Cost: €200.00) Host Mouse Application ELISA, Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€374,40 Add to cart
