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Dopamine Polyclonal
Description Dopamine is a catecholamine neurotransmitter expressed mainly in the brain that activates dopamine receptors. Dopamine is also a neurohormone released by the hypothalamus. Its chemical name is 4-(2-aminoethyl)benzene-1,2-diol, and its main function is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine can be used as a sympathomimetic drug because it produces effects such as increased heart rate and blood pressure. Changes in Dopamine concentration within the brain may explain symptoms observed in individuals with Schizophrenia, and a reduction in its concentration is associated with Parkinson's disease. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC) Reactivity Human 
1 ml more info 
14 days 
€494,00 Add to cart -
Dopamine Polyclonal
Description Dopamine is a catecholamine neurotransmitter expressed mainly in the brain that activates dopamine receptors. Dopamine is also a neurohormone released by the hypothalamus. Its chemical name is 4-(2-aminoethyl)benzene-1,2-diol, and its main function is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine can be used as a sympathomimetic drug because it produces effects such as increased heart rate and blood pressure. Changes in Dopamine concentration within the brain may explain symptoms observed in individuals with Schizophrenia, and a reduction in its concentration is associated with Parkinson's disease. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC) Reactivity Human
7 ml more info 14 days
€254,80 Add to cart -
FOXL1 Polyclonal
Description Forkhead box protein L1s or FKHL11, is encoded by the FOXL1 gene in human. FOXL1 protein belongs to the forehead box (Fox) family of transcription factors characterized by a common DNA-binding domain (the forkhead box). FOXL1 is involved in regulating the proliferation of gastrointestinal epithelial cells. Loss of Foxl1 leads to distorted architecture of the stomach and small intestine in mice due to a markedly increased epithelial proliferation. Foxl1 knockout is correlated with an enhanced Wnt/β-catenin pathway activation as evidenced by increased β-catenin nuclear localization. FOXL1 expression is down-regulated in the majority of human clear cell renal cell carcinoma (ccRCC), at both mRNA and protein levels. FOXL1 expression inversely correlates with the aggressive phenotype of ccRCC and the survival outcome of patients. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€494,00 Add to cart -
Histone H3 K27M Mutant/H3K27M [RM192]
Description Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Histone variant H3.3 is typically enriched in active chromatin. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunocytochemistry (ICC),Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat 
1 ml more info 14 days
€455,00 Add to cart -
IgG Gamma Polyclonal
Description Representing approximately 75% of serum immunoglobulins in humans, IgG is the most abundant antibody isotype found in the circulation. IgG molecules are synthesized and secreted by plasma B cells. IgG antibody reacts with the IgG human immunoglobulin gamma-chain. The antibody marks IgG contained in all plasma cells and their precursors, most of them follicular dendritic cells, centroblastic-centrocytic lymph cells and IgG secretory multiple myelomas. Generally, membrane bond immunoglobulins, connective tissue or blood vessels bond extracellular immunoglobulins and immunocomplex can only be shown on frozen tissues. Plasma cells may not be much stained on frozen tissues because immunoglobulins distribute diffusely by their cytoplasm. Anti-Human IgG gamma antibody is research for immunology, microbiology, and cancer. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€361,40 Add to cart -
IL-17 Polyclonal
Description Interleukin-17 is a protein that in humans is encoded by the IL17 gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappa B and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide. High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. Ligand for IL17RA. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (By similarity). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (By similarity). (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunofluorescence (IF) Immunohistochemistry (IHC) Reactivity Human
1 ml more info 14 days
€374,40 Add to cart -
IRAK2 Polyclonal
Description IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
1 ml more info 14 days
€494,00 Add to cart -
IRAK2 Polyclonal
Description IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human, Mouse, Rat
7 ml more info 14 days
€201,50 Add to cart -
LSM14A/RAP55 Polyclonal
Description The LSM14 domain and the RGG repeats of RAP55 are required for accumulation in P-bodies, and the region containing the FDF motif is responsible for cytoplasmic retention. RAP55, and all other Sm-like proteins, contain the Sm sequence motif, which consists of two regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSm14A is a key innate immunity component of the processing body (P-body) that mediates interferon-beta (IFN-beta) signaling by viral RNA. Knockdown of LSm14A inhibits cytosolic RNA-and DNA-trigger type I IFN production and cellular antiviral response. Moreover, LSm14A is essential for early-phase induction of IFN-beta after either RNA or DNA virus infection. chicken LSm14A (cLSm14A) is an important sensor that mediates innate immunity in the chicken against NDV infections. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€429,00 Add to cart -
Mycobacterium tuberculosis (MTB) Polyclonal
Description Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on the cell surface (primarily mycolic acid), which makes the cells impervious to Gram staining so acid-fast detection techniques are used instead. (Shipping Cost: €200.00) Host Rabbit Application ELISA, Immunohistochemistry (IHC), Western Blot (WB) Reactivity Human
1 ml more info 14 days
€374,40 Add to cart
