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CD7 [MD146]
| Product group: | Primary |
| Monoclonal/ Polyclonal: | Monoclonal |
| Clone: | CBC.37 |
| Host: | Mouse |
| Isotype: | IgG2b |
| Application: | Flow cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Application notes: | Prediluted |
| Conjugation Type: | Unconjugated |
| Lightchain type: | Kappa |
| Reactivity: | Human |
| General notes: | Localization: membrane. |
| Buffer: | citrate pH6.0 oe EDTA pH8.0 |
| UNSPSC code: | 12352203 |
CD7 is a single-pass type 1 transmembrane protein that is a member of the immunoglobulin superfamily. It plays an essential role in T-cell interactions and also in T-cell/B-cell interactions during early lymphoid development. CD7 is expressed on thymocytes, T- and natural killer cells, and progenitors of lymphoid and myeloid cells. It is also expressed on Tcell Acute Lymphoblastic Leukemia/Lymphoma, Acute Myelogenous Leukemia and Chronic Myelogenous Leukemia. CD7 antibody is the most sensitive and specific T-cell deletion marker. Loss of CD7 expression by neoplastic lymphocytes is considered a distinguishing characteristic of mycosis fungoides (MF) and cutaneous T-cell lymphoma. (Shipping Cost: €200.00)
CD7 [CBC.37]
CD7 is a single-pass type 1 transmembrane protein that is a member of the immunoglobulin superfamily. It plays an essential role in T-cell interactions and also in T-cell/B-cell interactions during early lymphoid development. CD7 is expressed on thymocytes, T- and natural killer cells, and progenitors of lymphoid and myeloid cells. It is also expressed on Tcell Acute Lymphoblastic Leukemia/Lymphoma, Acute Myelogenous Leukemia and Chronic Myelogenous Leukemia. CD7 antibody is the most sensitive and specific T-cell deletion marker. Loss of CD7 expression by neoplastic lymphocytes is considered a distinguishing characteristic of mycosis fungoides (MF) and cutaneous T-cell lymphoma.
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